17beta-hydroxy-5alpha-androstan-3-one
362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API
52 compounds within 3 steps: 5 in 1, 7 in 2, 40 in 3
Three steps
- steroid sulfatase (5-alpha-dihydrotestosterone)
- steroid sulfatase (5-alpha-dihydrotestosterone)
- Transport of 5-Hydroxyindoleacetate
Catalysed by STS, SLC4A1cytosol, extracellular spaceOne of 2 routes
- 17beta-hydroxy-5alpha-androstan-3-one + NAD(+) = 5alpha-androstan-3,17-dione + NADH + H(+)
- 5alpha-androstane-3,17-dione:NADP+ delta4-oxidoreductase
- androst-4-ene-3,17-dione + reduced [NADPH--hemoprotein reductase] + O2 = 6beta-hydroxyandrost-4-ene-3,17-dione + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by HSD17B2, HSD17B8, HSD17B10, DHRS9 and 3 morecytosol