spermatogenic failure
MONDO:0004983Mondo
Findings
No curated finding names spermatogenic failure yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A male infertility characterized by dirsuption of the process of sperm development from diploid cells into mature haploid spermatozoa.
Definition from the Mondo Disease Ontology (MONDO:0004983), read 2026-09-29. CC BY 4.0.
Genes
13 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- DMRT1HGNC:2934
- Definitive · ClinGen · Autosomal dominant · 2026
- DNAH12HGNC:2943
- Definitive · ClinGen · Autosomal recessive · 2025
- BCORL1HGNC:25657
- Strong · PanelApp Australia · X-linked · 2025
- DNAH6HGNC:2951
- Strong · ClinGen · Autosomal recessive · 2025
- Strong · PanelApp Australia · Autosomal recessive · 2025
- DZIP1HGNC:20908
- Moderate · PanelApp Australia · Autosomal recessive · 2025
- MYCBPAPHGNC:19677
- Moderate · Ambry Genetics · Autosomal recessive · 2024
- RHOXF1HGNC:29993
- Moderate · PanelApp Australia · X-linked · 2025
- RPL10LHGNC:17976
- Moderate · PanelApp Australia · Autosomal recessive · 2025
- AK7HGNC:20091
- Limited · ClinGen · Autosomal recessive · 2023
- DMC1HGNC:2927
- Limited · Ambry Genetics · Autosomal recessive · 2018
- NUP210LHGNC:29915
- Limited · Ambry Genetics · Autosomal recessive · 2025
- SHOC1HGNC:26535
- Limited · Franklin by Genoox · Autosomal recessive · 2020
- STX2HGNC:3403
- Limited · Ambry Genetics · Autosomal recessive · 2018
Where it sits
- Located in (Mondo)
- A kind of
- Narrower terms (113)
- spermatogenic failure 1
- spermatogenic failure 10
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- spermatogenic failure 2
- spermatogenic failure 3
- spermatogenic failure 30
- spermatogenic failure 31
- spermatogenic failure 32
- spermatogenic failure 33
- spermatogenic failure 34
- spermatogenic failure 35
- spermatogenic failure 36
- spermatogenic failure 4
- spermatogenic failure 47