spermatogenic failure 77
MONDO:0031083Mondo
Findings
No curated finding names spermatogenic failure 77 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- Autosomal recessive inheritance
- Onset and course
- Young adult onset
HPO, annotations 2026-09-02
Features
8 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Elevated circulating follicle stimulating hormone levelHPOHP:0008232
- 6 of 6 reported patients
- Male infertilityHPOHP:0003251
- 6 of 6 reported patients
- OligozoospermiaHPOHP:0000798
- 5 of 6 reported patients
- Multiflagellar spermatozoaHPOHP:0034309
- 3 of 4 reported patients
- CryptorchidismHPOHP:0000028
- 2 of 6 reported patients
- AzoospermiaHPOHP:0000027
- 1 of 6 reported patients
- Abnormal circulating luteinizing hormone concentrationHPOHP:0030345
- 0 of 6 reported patients
- Abnormal circulating testosterone concentrationHPOHP:0030087
- 0 of 6 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- FKBP6HGNC:3722
- Strong · PanelApp Australia · Autosomal recessive · 2025
- Moderate · Ambry Genetics · Autosomal recessive · 2023
Where it sits
- A kind of
Other names
1 name
Resolves to: spermatogenic failure 77
- Also called
- SPGF77