spermatogenic failure, X-linked, 4
MONDO:0024773Mondo
Findings
No curated finding names spermatogenic failure, X-linked, 4 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- X-linked inheritance
- Onset and course
- Young adult onset
HPO, annotations 2026-09-02
Features
6 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Male infertilityHPOHP:0003251
- 7 of 7 reported patients
- AzoospermiaHPOHP:0000027
- 5 of 7 reported patients
- Elevated circulating follicle stimulating hormone levelHPOHP:0008232
- 5 of 7 reported patients
- Decreased serum testosterone concentrationHPOHP:0040171
- 3 of 7 reported patients
- Elevated circulating luteinizing hormone levelHPOHP:0011969
- 1 of 7 reported patients
- Abnormal prolactin levelHPOHP:0040086
- 0 of 7 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- HGNC:15805HGNC:15805
- Strong · PanelApp Australia · X-linked · 2025
Where it sits
- A kind of
Other names
1 name
Resolves to: spermatogenic failure, X-linked, 4
- Also called
- SPGFX4