Compound

L-homocysteine thiolactone

CHEBI:233452ChEBI

Structure

2D depiction · 3D model shown

Loading the model…

A generated conformer of L-homocysteine thiolactone — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, cation
Formula: C4H8NOS
Mass: 118.181 g/mol
Charge: +1
InChIKey: KIWQWJKWBHZMDT-VKHMYHEASA-O
SMILES: [NH3+][C@H]1CCSC1=O
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

4 entities

4 entities reached.

0 reported hops4 assembled from the scaffold

What the reference databases state

Statements

9 statements

9 statements · 2 reference databases · Subject: L-homocysteine thiolactone · Sources: Human-GEM, Rhea

Order

homocysteine is converted to L-homocysteine thiolactoneCompoundHuman-GEM MAR03920Inferred only
L-homocysteine thiolactone is converted to homocysteineCompoundHuman-GEM MAR03920Inferred only
L-homocysteine thiolactone is converted to L-homocysteineCompoundRhea RHEA:83867Inferred only
L-homocysteine is converted to L-homocysteine thiolactoneCompoundRhea RHEA:83875Inferred only
L-homocysteinyl-AMP is converted to L-homocysteine thiolactoneCompoundRhea RHEA:83883Inferred only
L-homocysteine thiolactone is a substrate of BPHLProteinRhea RHEA:83867Inferred only
L-homocysteine thiolactone is a substrate of PON1ProteinHuman-GEM MAR03920Inferred only
L-homocysteine thiolactone is a substrate of PON2ProteinHuman-GEM MAR03920Inferred only
L-homocysteine thiolactone is a substrate of PON3ProteinHuman-GEM MAR03920Inferred only

Reactions

6 reactions

water+L-homocysteine thiolactoneproton+homocysteine
Catalysed by PON1 or PON3 or PON2
Reaction pageReversibleBalancedEC 3.1.1.2cytosol
Human-GEM MAR03920CC BY 4.0Reference data
L-homocysteine thiolactoneL-homocysteine thiolactone
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR11913CC BY 4.0Reference data
L-homocysteine thiolactone
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR11914CC BY 4.0Reference data
L-homocysteine thiolactone+waterL-homocysteine+hydron
Catalysed by BPHL
Reaction pageLeft to rightBalanced
Rhea RHEA:83867CC BY 4.0Reference data
L-homocysteine+ATP(4-)L-homocysteine thiolactone+AMP+diphosphate(3-)
Catalysed by MARS1
Reaction pageLeft to rightBalanced
Rhea RHEA:83875CC BY 4.0Reference data
L-homocysteinyl-AMPL-homocysteine thiolactone+AMP+hydron
Catalysed by MARS1
Reaction pageLeft to rightBalanced
Rhea RHEA:83883CC BY 4.0Reference data