Compound
a very-long-chain 3-oxoacyl-CoA
A 3-oxoacyl-CoA(4−) arising from deprotonation of the phosphate and diphosphate OH groups of any very long-chain 3-oxoacyl-CoA (very long-chain = chain length greater than C22); major species at pH 7.3.
Definition from ChEBI (CHEBI:90725), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C24H33N7O18P3SR
- Mass
- 832.543 g/mol
- Charge
- -4
- SMILES
- *C(=O)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Statements
4 statements
4 statements · 1 reference database · Subject: a very-long-chain 3-oxoacyl-CoA · Sources: Rhea
- a very-long-chain 3-oxoacyl-CoA is converted to a very long-chain fatty acyl-CoACompoundRhea RHEA:78895Inferred only
- a very-long-chain acyl-CoA is converted to a very-long-chain 3-oxoacyl-CoACompoundRhea RHEA:32727Inferred only
- a very-long-chain 3-oxoacyl-CoA is a substrate of ACAA1ProteinRhea RHEA:78895Inferred only
- a very-long-chain 3-oxoacyl-CoA is a substrate of HSD17B12ProteinRhea RHEA:48680Inferred only
Reactions
5 reactions
a very-long-chain acyl-CoA+malonyl-CoA+hydrona very-long-chain 3-oxoacyl-CoA+carbon dioxide+coenzyme A(4-)
Catalysed by ELOVL7 or ELOVL1 or ELOVL4 or ELOVL6 or ELOVL3 or ELOVL2 or ELOVL5
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:32727CC BY 4.0Reference data
CHEBI:85440+NADP(3-)a very-long-chain 3-oxoacyl-CoA+NADPH(4-)+hydron
Catalysed by HSD17B12
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:48680CC BY 4.0Reference data
CHEBI:85440+NAD(1-)a very-long-chain 3-oxoacyl-CoA+NADH(2-)+hydron
Catalysed by HSD17B4
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:78871CC BY 4.0Reference data
a very long-chain fatty acyl-CoA+acetyl-CoAa very-long-chain 3-oxoacyl-CoA+coenzyme A(4-)
Catalysed by ACAA1
Reaction pageRight to leftBalance undeterminable
Rhea RHEA:78895CC BY 4.0Reference data
CHEBI:229600+NAD(1-)a very-long-chain 3-oxoacyl-CoA+NADH(2-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:78927CC BY 4.0Reference data
Other names
1 name
Resolves to: a very-long-chain 3-oxoacyl-CoA
- Also called
- very long-chain 3-oxoacyl-CoA(4-)