Compound
2''-O-acetyl-ADP-D-ribose
A nucleotide-sugar oxoanion arising from deprotonation of the diphosphate OH groups of 2''-O-acetyl-ADP-D-ribose; major species at pH 7.3.
Definition from ChEBI (CHEBI:83767), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C17H23N5O15P2
- Mass
- 599.339 g/mol
- Charge
- -2
- InChIKey
- BFNOPXRXIQJDHO-YDKGJHSESA-L
- SMILES
- CC(=O)O[C@H]1C(O)O[C@H](COP(=O)([O-])OP(=O)([O-])OC[C@H]2O[C@@H](n3cnc4c(N)ncnc43)[C@H](O)[C@@H]2O)[C@H]1O
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Statements
6 statements
6 statements · 2 reference databases · Subject: 2''-O-acetyl-ADP-D-ribose · Sources: Human-GEM, Rhea
- 2''-O-acetyl-ADP-D-ribose is a substrate of MACROD1ProteinHuman-GEM MAR20099Inferred only
- 2''-O-acetyl-ADP-D-ribose is a substrate of MACROD1ProteinRhea RHEA:57060Inferred only
- 2''-O-acetyl-ADP-D-ribose is a substrate of MACROD2ProteinHuman-GEM MAR20099Inferred only
- 2''-O-acetyl-ADP-D-ribose is a substrate of MACROD2ProteinRhea RHEA:57060Inferred only
- 2''-O-acetyl-ADP-D-ribose is a substrate of OARD1ProteinHuman-GEM MAR20099Inferred only
- 2''-O-acetyl-ADP-D-ribose is a substrate of OARD1ProteinRhea RHEA:57060Inferred only
Reactions
3 reactions
water+2''-O-acetyl-ADP-D-riboseacetate+ADP-D-ribose+proton
Catalysed by MACROD2 or MACROD1 or OARD1
Reaction pageLeft to rightBalancedEC 3.1.1.106nucleus
Human-GEM MAR20099CC BY 4.0Reference data
N(6)-acetyl-L-lysyl-[protein]+NAD(1-)+water2''-O-acetyl-ADP-D-ribose+nicotinamide+L-lysyl-[protein]
Catalysed by SIRT2 or SIRT6 or SIRT1 or SIRT7 or SIRT3 or SIRT4
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:43636CC BY 4.0Reference data
2''-O-acetyl-ADP-D-ribose+waterADP-D-ribose+acetate+hydron
Catalysed by MACROD2 or MACROD1 or OARD1
Reaction pageLeft to rightBalanced
Rhea RHEA:57060CC BY 4.0Reference data