Papers/PMID:41617950
Effects of Zinc Supplementation on Anthropometric Indices and Adipokines in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Biological trace element research2026The record
5 findings · 1 compound · 5 endpoints · 4 null
What it reported
How to read these marksWhat moved
1 finding
Zn(2+) — decreases waist circumference
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“However, zinc supplementation was associated with a significant increase in body weight (BW) (WMD: 0.68 kg; 95% CI: 0.33 to 1.03; p < 0.001) and a reduction in waist circumference (WC) (WMD: −1.03 cm; 95% CI: −1.92 to − 0.13; p = 0.025).”
Quoted verbatim from Effects of Zinc Supplementation on Anthropometric Indices and Adipokines in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.. - Study
- meta-analysis
- Population
- Adults in randomised controlled trials of zinc supplementation (pooled, general population)
Effect -1.03 mean difference, 95% CI -1.92 to -0.13
Effects of Zinc Supplementation on Anthropometric Indices and Adipokines in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.2026PMID:41617950Permalink
What did not
4 findings
Zn(2+) — no detected effect on fat mass
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“A meta-analysis of 41 RCTs (44 effect sizes) indicated that zinc supplementation had no significant overall effect on body mass index (BMI) (WMD: 0.02 kg/m²; p = 0.889), fat mass (FM) (WMD: −0.08 kg; p = 0.794), fat-free mass (FFM) (WMD: 0.41 kg; p = 0.669), adiponectin (WMD: 1.27 µg/mL; p = 0.184), or leptin (WMD: 1.82 ng/mL; p = 0.165).”
Quoted verbatim from Effects of Zinc Supplementation on Anthropometric Indices and Adipokines in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.. - Study
- meta-analysis
- Population
- Adults in randomised controlled trials of zinc supplementation (pooled, general population)
Effects of Zinc Supplementation on Anthropometric Indices and Adipokines in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.2026PMID:41617950Permalink
Zn(2+) — no detected effect on lean body mass
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“A meta-analysis of 41 RCTs (44 effect sizes) indicated that zinc supplementation had no significant overall effect on body mass index (BMI) (WMD: 0.02 kg/m²; p = 0.889), fat mass (FM) (WMD: −0.08 kg; p = 0.794), fat-free mass (FFM) (WMD: 0.41 kg; p = 0.669), adiponectin (WMD: 1.27 µg/mL; p = 0.184), or leptin (WMD: 1.82 ng/mL; p = 0.165).”
Quoted verbatim from Effects of Zinc Supplementation on Anthropometric Indices and Adipokines in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.. - Study
- meta-analysis
- Population
- Adults in randomised controlled trials of zinc supplementation (pooled, general population)
Effects of Zinc Supplementation on Anthropometric Indices and Adipokines in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.2026PMID:41617950Permalink
Zn(2+) — no detected effect on body mass index
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“A meta-analysis of 41 RCTs (44 effect sizes) indicated that zinc supplementation had no significant overall effect on body mass index (BMI) (WMD: 0.02 kg/m²; p = 0.889), fat mass (FM) (WMD: −0.08 kg; p = 0.794), fat-free mass (FFM) (WMD: 0.41 kg; p = 0.669), adiponectin (WMD: 1.27 µg/mL; p = 0.184), or leptin (WMD: 1.82 ng/mL; p = 0.165).”
Quoted verbatim from Effects of Zinc Supplementation on Anthropometric Indices and Adipokines in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.. - Study
- meta-analysis
- Population
- Adults in randomised controlled trials of zinc supplementation (pooled, general population)
Effects of Zinc Supplementation on Anthropometric Indices and Adipokines in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.2026PMID:41617950Permalink
Zn(2+) — no detected effect on serum leptin
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull resultreplicated ×1“A meta-analysis of 41 RCTs (44 effect sizes) indicated that zinc supplementation had no significant overall effect on body mass index (BMI) (WMD: 0.02 kg/m²; p = 0.889), fat mass (FM) (WMD: −0.08 kg; p = 0.794), fat-free mass (FFM) (WMD: 0.41 kg; p = 0.669), adiponectin (WMD: 1.27 µg/mL; p = 0.184), or leptin (WMD: 1.82 ng/mL; p = 0.165).”
Quoted verbatim from Effects of Zinc Supplementation on Anthropometric Indices and Adipokines in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.. - Study
- meta-analysis
- Population
- Adults in randomised controlled trials of zinc supplementation (pooled, general population)
Effects of Zinc Supplementation on Anthropometric Indices and Adipokines in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.2026PMID:41617950Permalink