Endpoint
Waist circumference
CAT:outcome/waist-circumferencereported in cm2 findings from 2 compounds
What moved it
How to read these marks2 findings · 2 compounds · 1 null · by evidence strength
| Compound | Direction | Findings | Strongest evidence |
|---|---|---|---|
| chromium(3+) | no effect | 1 | Evidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited. |
| Ca(2+) | down | 1 | Evidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence. |
Reported to move it
1 finding
Ca(2+) — decreases
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“Moderate-certainty evidence shows that calcium supplementation compared to placebo or control probably results in a small reduction in body mass index (BMI) (MD -0.18 kg/m2,95% CI -0.22 to -0.13; P < 0.001, I2 = 0%; 9 studies, 731 participants) and waist circumference (MD -0.51 cm, 95% CI -0.72 to -0.29; P < 0.001, I2 = 0%; 6 studies, 273 participants).”
Quoted verbatim from Calcium supplementation for people with overweight or obesity.. - Study
- meta-analysis
- Participants
- 273
- Dose
- 0.162 to 1.5 g calcium per day across trials
- Population
- People with overweight or obesity in 6 randomised trials of oral calcium supplementation versus placebo or control (abstract only)
Effect -0.51 mean difference, 95% CI -0.72 to -0.29
Calcium supplementation for people with overweight or obesity.2024PMID:38721870Permalink
Measured, no effect detected
1 finding
chromium(3+) — no detected effect on
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.FindingNull result“Six months of chromium supplementation (500 mcg or 1000 mcg) was not associated with any significant changes in glycohemoglobin, weight, waist circumference, BMI, blood pressure, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, or urine microalbumin compared with placebo.”
Quoted verbatim from Chromium effects on glucose tolerance and insulin sensitivity in persons at risk for diabetes mellitus.. - Study
- crossover
- Duration
- 6 months
- Dose
- chromium picolinate 500 mcg or 1000 mcg daily
- Population
- Adults with impaired glucose tolerance, impaired fasting glucose or metabolic syndrome, without diabetes; modified cross-over, 6 months of chromium picolinate versus placebo
Chromium effects on glucose tolerance and insulin sensitivity in persons at risk for diabetes mellitus.2011PMID:20634174Industry fundedPermalink
How it is measured
Girth of the waist by tape measure at the landmark the source protocol states (midpoint between lowest rib and iliac crest, umbilical level or narrowest point), in centimetres.
Measured, not recorded
- Subject
- waist circumference
- Measurements
- 13 measurements
- Recorded as a finding
- No
Show what was measured
waist circumference
decreases, p = 0.008
waist circumference (93 ± 8.9 vs. 83 + 8.6 cm, P = .008)
PMID:28598231 · one of two readings recorded this
Waist circumference
decreases, p = 0.001
The results of the meta-analysis displayed a significant reduction in WC following L-arginine supplementation (WMD: -2.97 cm; 95% CI: -4.75 to -1.18, P = 0.001)
PMID:30982445 · one of two readings recorded this
waist circumference
no effect
waist circumference (WMD: 0.12, 95% CI: - 1.24 to 1.48)
PMID:32385715 · one of two readings recorded this
waist circumference
no effect
No significant change was observed in bodyweight, WC, BF percentage and WHR as compared to controls
PMID:32654500 · one of two readings recorded this
waist circumference
no effect
no significant effects between groups were observed for waist circumference and other secondary outcomes
PMID:34330458 · one of two readings recorded this
Waist circumference
no effect, p = 0.35
WC (cm) | 100.5 ± 11.3 | 99.7 ± 11.8 | − 0.9 ± 2.8 | 0.06 | 100.6 ± 6.3 | 100.3 ± 6.7 | − 0.3 ± 1.9 | 0.44 | 0.35
PMID:36307427 · one of two readings recorded this
Waist circumference
no effect, p = 0.35, n = 44
Baseline | 94.85 ± 9.24 | − 1.32 ± 3.76 | 90.87 ± 8.88 | − 0.26 ± 1.73 | 0.35
PMID:37078370 · one of two readings recorded this
Waist circumference
decreases, p = 0.012, n = 46
body mass index (BMI), body weight, and neck, waist, and hip circumferences (p < 0.001, <0.001, <0.001, = 0.012, and =0.030, respectively)
PMID:37929031 · one of two readings recorded this
waist circumference
decreases, p = 0.00001
[MD = -7.71, 95% CI (-10.17, -5.25), p < 0.00001]
PMID:38356942 · one of two readings recorded this
waist circumference
decreases, p = 0.00001
[MD = -4.08, 95% CI (-5.77, -2.39), p < 0.00001]
PMID:38356942 · one of two readings recorded this
waist circumference
decreases, p = 0.001, n = 273
(MD -0.51 cm, 95% CI -0.72 to -0.29; P < 0.001, I2 = 0%; 6 studies, 273 participants)
PMID:38721870 · one of two readings recorded this
waist circumference
no effect
UA supplementation didn't significantly change body weight, body mass index, waist circumference, body fat percentage, lean body mass
PMID:38923885 · one of two readings recorded this
waist circumference
decreases
WC (SMD - 0.91, 95% CI - 1.14 to - 0.69)
PMID:39037553 · one of two readings recorded this
Sources cited
2 papers
- Subject
- waist circumference
- Findings
- 2
- Papers
- 2