Papers/PMID:40048139
Cardioprotective Effect of Nigella sativa in Pediatric Patients with Type 1 Diabetes Mellitus: A Randomized Controlled Study.
Paediatric drugs2025The record
4 findings · 1 compound · 4 endpoints
What it reported
How to read these marksWhat moved
4 findings
Nigella sativa — decreases total cholesterol (TC)
Evidence strength: moderate.Finding“The mean level of cholesterol and LDL-C was significantly lower in group I than in group II after treatment.”
Quoted verbatim from Cardioprotective Effect of Nigella sativa in Pediatric Patients with Type 1 Diabetes Mellitus: A Randomized Controlled Study.. - Study
- RCT
- Dose
- 450 mg twice daily after meals for 3 months, in addition to insulin
- Population
- Children and adolescents aged 10 to 18 years with type 1 diabetes; insulin continued in both arms, control received insulin alone
Cardioprotective Effect of Nigella sativa in Pediatric Patients with Type 1 Diabetes Mellitus: A Randomized Controlled Study.2025PMID:4004813910.1007/s40272-025-00687-5Permalink
Nigella sativa — decreases malondialdehyde (circulating)
Evidence strength: moderate.Finding“In addition, the mean levels of MDA, nitric oxide, TNF-α, TGF-β, and troponin I were significantly lower in group I than in group II.”
Quoted verbatim from Cardioprotective Effect of Nigella sativa in Pediatric Patients with Type 1 Diabetes Mellitus: A Randomized Controlled Study.. - Study
- RCT
- Dose
- 450 mg twice daily after meals for 3 months, in addition to insulin
- Population
- Children and adolescents aged 10 to 18 years with type 1 diabetes; insulin continued in both arms, control received insulin alone
Cardioprotective Effect of Nigella sativa in Pediatric Patients with Type 1 Diabetes Mellitus: A Randomized Controlled Study.2025PMID:4004813910.1007/s40272-025-00687-5Permalink
Nigella sativa — decreases tumour necrosis factor alpha concentration
Evidence strength: moderate.Finding“In addition, the mean levels of MDA, nitric oxide, TNF-α, TGF-β, and troponin I were significantly lower in group I than in group II.”
Quoted verbatim from Cardioprotective Effect of Nigella sativa in Pediatric Patients with Type 1 Diabetes Mellitus: A Randomized Controlled Study.. - Study
- RCT
- Dose
- 450 mg twice daily after meals for 3 months, in addition to insulin
- Population
- Children and adolescents aged 10 to 18 years with type 1 diabetes; insulin continued in both arms, control received insulin alone
Cardioprotective Effect of Nigella sativa in Pediatric Patients with Type 1 Diabetes Mellitus: A Randomized Controlled Study.2025PMID:4004813910.1007/s40272-025-00687-5Permalink
Nigella sativa — decreases LDL cholesterol
Evidence strength: moderate.Finding“The mean level of cholesterol and LDL-C was significantly lower in group I than in group II after treatment.”
Quoted verbatim from Cardioprotective Effect of Nigella sativa in Pediatric Patients with Type 1 Diabetes Mellitus: A Randomized Controlled Study.. - Study
- RCT
- Dose
- 450 mg twice daily after meals for 3 months, in addition to insulin
- Population
- Children and adolescents aged 10 to 18 years with type 1 diabetes; insulin continued in both arms, control received insulin alone
Cardioprotective Effect of Nigella sativa in Pediatric Patients with Type 1 Diabetes Mellitus: A Randomized Controlled Study.2025PMID:4004813910.1007/s40272-025-00687-5Permalink