Papers/PMID:31625814
The Evidence and Controversy Between Dietary Calcium Intake and Calcium Supplementation and the Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Cohort Studies and Randomized Controlled Trials.
Journal of the American College of Nutrition2020The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
Ca(2+) — increases incidence of myocardial infarction
Evidence strength: very limited.Findingreplicated ×2“CSs increased the risk of myocardial infarction (MI) by 14% (RR = 1.14, 95% CI, 1.05-1.25; I2 = 0.0%), and CSs alone increased the MI risk 21% (RR = 1.21, 95% CI, 1.08-1.35; I2 = 0.0%).”
Quoted verbatim from The Evidence and Controversy Between Dietary Calcium Intake and Calcium Supplementation and the Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Cohort Studies and Randomized Controlled Trials.. - Study
- meta-analysis
- Population
- Pooled randomised controlled trials of calcium supplements (CSs), with or without vitamin D; the second estimate is calcium supplements alone
The Evidence and Controversy Between Dietary Calcium Intake and Calcium Supplementation and the Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Cohort Studies and Randomized Controlled Trials.2020PMID:3162581410.1080/07315724.2019.1649219Permalink
Ca(2+) — increases incidence of coronary heart disease
Evidence strength: very limited.Finding“Pooled RR of RCTs showed that the risk of CHD due to calcium supplements (CSs) increased 8% (RR = 1.08, 95% CI, 1.02-1.22; I2 = 0.0%) and increased 20% allocated to CSs alone (RR = 1.20, 95% CI, 1.08-1.33; I2 = 0.0%).”
Quoted verbatim from The Evidence and Controversy Between Dietary Calcium Intake and Calcium Supplementation and the Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Cohort Studies and Randomized Controlled Trials.. - Study
- meta-analysis
- Population
- Pooled randomised controlled trials of calcium supplements (CSs), with or without vitamin D; the second estimate is calcium supplements alone
The Evidence and Controversy Between Dietary Calcium Intake and Calcium Supplementation and the Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Cohort Studies and Randomized Controlled Trials.2020PMID:3162581410.1080/07315724.2019.1649219Permalink