Papers/PMID:23289009
Effects of zinc supplementation on plasma copper/zinc ratios, oxidative stress, and immunological status in hemodialysis patients.
International journal of medical sciences2013The record
5 findings · 1 compound · 5 endpoints
What it reported
How to read these marksWhat moved
5 findings
Zn(2+) — decreases C-reactive protein concentration
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×5“After the treatment period, the Zn-supplemented patients had significantly decreased concentrations of hs-CRP, TNF-α, and IL-1β compared to patients not receiving Zn supplementation.”
Quoted verbatim from Effects of zinc supplementation on plasma copper/zinc ratios, oxidative stress, and immunological status in hemodialysis patients.. - Study
- RCT
- Duration
- 8 weeks
- Dose
- 11 mg elemental Zn per day (78 mg Zn gluconate), after dinner
- Population
- Long-term hemodialysis patients with low plasma zinc, supplemented for eight weeks versus patients given no supplement
Effects of zinc supplementation on plasma copper/zinc ratios, oxidative stress, and immunological status in hemodialysis patients.2013PMID:23289009Permalink
Zn(2+) — increases blood haemoglobin concentration
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“After eight weeks, HD patients receiving Zn supplementation had markedly higher nPNA, hemoglobin, and albumin concentrations, as well as higher eGFR, than patients who did not receive Zn supplements.”
Quoted verbatim from Effects of zinc supplementation on plasma copper/zinc ratios, oxidative stress, and immunological status in hemodialysis patients.. - Study
- RCT
- Duration
- 8 weeks
- Dose
- 11 mg elemental Zn per day (78 mg Zn gluconate), after dinner
- Population
- Long-term hemodialysis patients with low plasma zinc, supplemented for eight weeks versus patients given no supplement
Effects of zinc supplementation on plasma copper/zinc ratios, oxidative stress, and immunological status in hemodialysis patients.2013PMID:23289009Permalink
Zn(2+) — increases serum albumin
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“After eight weeks, HD patients receiving Zn supplementation had markedly higher nPNA, hemoglobin, and albumin concentrations, as well as higher eGFR, than patients who did not receive Zn supplements.”
Quoted verbatim from Effects of zinc supplementation on plasma copper/zinc ratios, oxidative stress, and immunological status in hemodialysis patients.. - Study
- RCT
- Duration
- 8 weeks
- Dose
- 11 mg elemental Zn per day (78 mg Zn gluconate), after dinner
- Population
- Long-term hemodialysis patients with low plasma zinc, supplemented for eight weeks versus patients given no supplement
Effects of zinc supplementation on plasma copper/zinc ratios, oxidative stress, and immunological status in hemodialysis patients.2013PMID:23289009Permalink
Zn(2+) — increases estimated glomerular filtration rate
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“After eight weeks, HD patients receiving Zn supplementation had markedly higher nPNA, hemoglobin, and albumin concentrations, as well as higher eGFR, than patients who did not receive Zn supplements.”
Quoted verbatim from Effects of zinc supplementation on plasma copper/zinc ratios, oxidative stress, and immunological status in hemodialysis patients.. - Study
- RCT
- Duration
- 8 weeks
- Dose
- 11 mg elemental Zn per day (78 mg Zn gluconate), after dinner
- Population
- Long-term hemodialysis patients with low plasma zinc, supplemented for eight weeks versus patients given no supplement
Effects of zinc supplementation on plasma copper/zinc ratios, oxidative stress, and immunological status in hemodialysis patients.2013PMID:23289009Permalink
Zn(2+) — decreases tumour necrosis factor alpha concentration
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×1“After the treatment period, the Zn-supplemented patients had significantly decreased concentrations of hs-CRP, TNF-α, and IL-1β compared to patients not receiving Zn supplementation.”
Quoted verbatim from Effects of zinc supplementation on plasma copper/zinc ratios, oxidative stress, and immunological status in hemodialysis patients.. - Study
- RCT
- Duration
- 8 weeks
- Dose
- 11 mg elemental Zn per day (78 mg Zn gluconate), after dinner
- Population
- Long-term hemodialysis patients with low plasma zinc, supplemented for eight weeks versus patients given no supplement
Effects of zinc supplementation on plasma copper/zinc ratios, oxidative stress, and immunological status in hemodialysis patients.2013PMID:23289009Permalink