Papers/PMID:16978367
Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trials.
Diabetic medicine : a journal of the British Diabetic Association2006The record
6 findings drawn from this paper, on 1 compound across 6 endpoints, 4 of them null.
What it reported
How to read these marksWhat moved
2 findings
magnesium(2+) — increases HDL cholesterol
PreliminaryGrade D, Preliminary. Non-human or in vitro only.Finding“Magnesium supplementation increased on high-density lipoprotein (HDL) cholesterol levels [0.08 mmol/l (95% CI, 0.03 to 0.14); P for heterogeneity = 0.36] but had no effect on total cholesterol, low-density lipoprotein (LDL) cholesterol and triglyceride.”
Quoted verbatim from Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trials.. - Study
- meta-analysis
- Dose
- 15 mmol/day (360 mg/day) oral magnesium, median
- Population
- Adults with type 2 diabetes in randomized double-blind controlled trials of oral magnesium supplementation
Effect 0.08 mean difference, 95% CI 0.03 to 0.14
Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trials.2006PMID:16978367
magnesium(2+) — decreases fasting blood glucose
PreliminaryGrade D, Preliminary. Non-human or in vitro only.Findingreplicated ×4“After a median duration of 12 weeks, the weighted mean post-intervention fasting glucose was significantly lower in the treatment groups compared with the placebo groups [-0.56 mmol/l (95% CI, -1.10 to -0.01); P for heterogeneity = 0.02].”
Quoted verbatim from Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trials.. - Study
- meta-analysis
- Duration
- 3 months
- Dose
- 15 mmol/day (360 mg/day) oral magnesium, median
- Population
- Adults with type 2 diabetes in randomized double-blind controlled trials of oral magnesium supplementation
Effect -0.56 mean difference, 95% CI -1.1 to -0.01
Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trials.2006PMID:16978367
What did not
4 findings
magnesium(2+) — no detected effect on systolic blood pressure (setting unspecified)
PreliminaryGrade D, Preliminary. Non-human or in vitro only.FindingNull result“Neither systolic nor diastolic BP was significantly changed.”
Quoted verbatim from Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trials.. - Study
- meta-analysis
- Dose
- 15 mmol/day (360 mg/day) oral magnesium, median
- Population
- Adults with type 2 diabetes in randomized double-blind controlled trials of oral magnesium supplementation
Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trials.2006PMID:16978367
magnesium(2+) — no detected effect on total cholesterol (TC)
PreliminaryGrade D, Preliminary. Non-human or in vitro only.FindingNull resultreplicated ×1“Magnesium supplementation increased on high-density lipoprotein (HDL) cholesterol levels [0.08 mmol/l (95% CI, 0.03 to 0.14); P for heterogeneity = 0.36] but had no effect on total cholesterol, low-density lipoprotein (LDL) cholesterol and triglyceride.”
Quoted verbatim from Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trials.. - Study
- meta-analysis
- Dose
- 15 mmol/day (360 mg/day) oral magnesium, median
- Population
- Adults with type 2 diabetes in randomized double-blind controlled trials of oral magnesium supplementation
Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trials.2006PMID:16978367
magnesium(2+) — no detected effect on LDL cholesterol
PreliminaryGrade D, Preliminary. Non-human or in vitro only.FindingNull result“Magnesium supplementation increased on high-density lipoprotein (HDL) cholesterol levels [0.08 mmol/l (95% CI, 0.03 to 0.14); P for heterogeneity = 0.36] but had no effect on total cholesterol, low-density lipoprotein (LDL) cholesterol and triglyceride.”
Quoted verbatim from Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trials.. - Study
- meta-analysis
- Dose
- 15 mmol/day (360 mg/day) oral magnesium, median
- Population
- Adults with type 2 diabetes in randomized double-blind controlled trials of oral magnesium supplementation
Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trials.2006PMID:16978367
magnesium(2+) — no detected effect on diastolic blood pressure (setting unspecified)
PreliminaryGrade D, Preliminary. Non-human or in vitro only.FindingNull result“Neither systolic nor diastolic BP was significantly changed.”
Quoted verbatim from Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trials.. - Study
- meta-analysis
- Dose
- 15 mmol/day (360 mg/day) oral magnesium, median
- Population
- Adults with type 2 diabetes in randomized double-blind controlled trials of oral magnesium supplementation
Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trials.2006PMID:16978367