Papers/NCT01114373
Melatonin and Nighttime Blood Pressure in African Americans--24 mg Study
ClinicalTrials.gov2015The record
5 findings drawn from this paper, on 1 compound across 4 endpoints, 5 of them null.
What it reported
How to read these marksEvery finding here is a null result.
What did not
5 findings
melatonin — no detected effect on mean arterial pressure
SuggestiveGrade C, Suggestive. Weak human evidence, or strong evidence in a mismatched population.FindingNull resultreplicated ×1“Mean Nighttime Mean Arterial Pressure (MAP) (SECONDARY, mmHg) -- NCT01114373: Melatonin 93.9 +/-1.8 (n=36) vs Placebo 94.4 +/-1.8 (n=36); difference -0.5; p=0.91, no significant difference”
Quoted verbatim from Melatonin and Nighttime Blood Pressure in African Americans--24 mg Study. - Study
- crossover
- Participants
- 72
- Population
- Hypertension; 18 Years+
Effect -0.5 mean difference
Melatonin and Nighttime Blood Pressure in African Americans--24 mg Study2015NCT01114373
melatonin — no detected effect on systolic blood pressure (setting unspecified)
SuggestiveGrade C, Suggestive. Weak human evidence, or strong evidence in a mismatched population.FindingNull resultreplicated ×1“Mean Daytime Systolic Blood Pressure (SBP) (SECONDARY, mmHg) -- NCT01114373: Melatonin 134.2 +/-2.4 (n=36) vs Placebo 137.3 +/-2.4 (n=36); difference -3.1; p=0.16, no significant difference”
Quoted verbatim from Melatonin and Nighttime Blood Pressure in African Americans--24 mg Study. - Study
- crossover
- Participants
- 72
- Population
- Hypertension; 18 Years+
Effect -3.1 mean difference
Melatonin and Nighttime Blood Pressure in African Americans--24 mg Study2015NCT01114373
melatonin — no detected effect on diastolic blood pressure (setting unspecified)
SuggestiveGrade C, Suggestive. Weak human evidence, or strong evidence in a mismatched population.FindingNull resultreplicated ×1“Mean Daytime Diastolic Blood Pressure (DBP) (SECONDARY, mmHg) -- NCT01114373: Melatonin 85.3 +/-1.8 (n=36) vs Placebo 86.6 +/-1.8 (n=36); difference -1.3; p=0.12, no significant difference”
Quoted verbatim from Melatonin and Nighttime Blood Pressure in African Americans--24 mg Study. - Study
- crossover
- Participants
- 72
- Population
- Hypertension; 18 Years+
Effect -1.3 mean difference
Melatonin and Nighttime Blood Pressure in African Americans--24 mg Study2015NCT01114373
melatonin — no detected effect on mean arterial pressure
SuggestiveGrade C, Suggestive. Weak human evidence, or strong evidence in a mismatched population.FindingNull resultreplicated ×1“Mean Daytime Mean Arterial Pressure (MAP) (SECONDARY, mmHg) -- NCT01114373: Melatonin 101.26 +/-1.9 (n=36) vs Placebo 103.5 +/-1.9 (n=36); difference -2.24; p=0.12, no significant difference”
Quoted verbatim from Melatonin and Nighttime Blood Pressure in African Americans--24 mg Study. - Study
- crossover
- Participants
- 72
- Population
- Hypertension; 18 Years+
Effect -2.24 mean difference
Melatonin and Nighttime Blood Pressure in African Americans--24 mg Study2015NCT01114373
melatonin — no detected effect on total sleep time
SuggestiveGrade C, Suggestive. Weak human evidence, or strong evidence in a mismatched population.FindingNull resultreplicated ×2“Total Sleep Time (SECONDARY, minutes) -- NCT01114373: Melatonin 415.8 +/-10.9 (n=36) vs Placebo 413.4 +/-10.6 (n=36); difference 2.4; p=0.39, no significant difference”
Quoted verbatim from Melatonin and Nighttime Blood Pressure in African Americans--24 mg Study. - Study
- crossover
- Participants
- 72
- Population
- Hypertension; 18 Years+
Effect 2.4 mean difference
Melatonin and Nighttime Blood Pressure in African Americans--24 mg Study2015NCT01114373