Papers/NCT01114360
Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study
ClinicalTrials.gov2015The record
6 findings drawn from this paper, on 1 compound across 4 endpoints, 6 of them null.
What it reported
How to read these marksEvery finding here is a null result.
What did not
6 findings
melatonin — no detected effect on systolic blood pressure (setting unspecified)
SuggestiveGrade C, Suggestive. Weak human evidence, or strong evidence in a mismatched population.FindingNull resultreplicated ×1“Mean Daytime Systolic Blood Pressure (SBP) (SECONDARY, mmHg) -- NCT01114360: Melatonin 135.13 +/-2.2 (n=36) vs Placebo 133.9 +/-2.2 (n=36); difference 1.23; p=0.64, no significant difference”
Quoted verbatim from Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study. - Study
- crossover
- Participants
- 72
- Population
- Hypertension; 18 Years+
Effect 1.23 mean difference
Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study2015NCT01114360
melatonin — no detected effect on diastolic blood pressure (setting unspecified)
SuggestiveGrade C, Suggestive. Weak human evidence, or strong evidence in a mismatched population.FindingNull resultreplicated ×1“Mean Daytime Diastolic Blood Pressure (DBP) (SECONDARY, mmHg) -- NCT01114360: Melatonin 85.7 +/-1.6 (n=36) vs Placebo 86.2 +/-1.7 (n=36); difference -0.5; p=0.89, no significant difference”
Quoted verbatim from Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study. - Study
- crossover
- Participants
- 72
- Population
- Hypertension; 18 Years+
Effect -0.5 mean difference
Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study2015NCT01114360
melatonin — no detected effect on diastolic blood pressure (setting unspecified)
SuggestiveGrade C, Suggestive. Weak human evidence, or strong evidence in a mismatched population.FindingNull resultreplicated ×1“Mean Nighttime Diastolic Blood Pressure (DBP) (PRIMARY, mmHg) -- NCT01114360: Melatonin 76 +/-1.7 (n=36) vs Placebo 76.2 +/-1.8 (n=36); difference -0.2; p=0.75, no significant difference”
Quoted verbatim from Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study. - Study
- crossover
- Participants
- 72
- Population
- Hypertension; 18 Years+
Effect -0.2 mean difference
Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study2015NCT01114360
melatonin — no detected effect on total sleep time
SuggestiveGrade C, Suggestive. Weak human evidence, or strong evidence in a mismatched population.FindingNull resultreplicated ×2“Total Sleep Time (SECONDARY, minutes) -- NCT01114360: Melatonin 399.8 +/-11.0 (n=36) vs Placebo 412.2 +/-11.1 (n=36); difference -12.4; p=0.52, no significant difference”
Quoted verbatim from Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study. - Study
- crossover
- Participants
- 72
- Population
- Hypertension; 18 Years+
Effect -12.4 mean difference
Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study2015NCT01114360
melatonin — no detected effect on mean arterial pressure
SuggestiveGrade C, Suggestive. Weak human evidence, or strong evidence in a mismatched population.FindingNull resultreplicated ×1“Mean Daytime Mean Arterial Pressure (MAP) (SECONDARY, mmHg) -- NCT01114360: Melatonin 102.2 +/-1.7 (n=36) vs Placebo 102.1 +/-1.8 (n=36); difference 0.1; p=0.97, no significant difference”
Quoted verbatim from Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study. - Study
- crossover
- Participants
- 72
- Population
- Hypertension; 18 Years+
Effect 0.1 mean difference
Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study2015NCT01114360
melatonin — no detected effect on mean arterial pressure
SuggestiveGrade C, Suggestive. Weak human evidence, or strong evidence in a mismatched population.FindingNull resultreplicated ×1“Mean Nighttime Mean Arterial Pressure (MAP) (SECONDARY, mmHg) -- NCT01114360: Melatonin 92.9 +/-1.9 (n=36) vs Placebo 92.6 +/-2.0 (n=36); difference 0.3; p=0.79, no significant difference”
Quoted verbatim from Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study. - Study
- crossover
- Participants
- 72
- Population
- Hypertension; 18 Years+
Effect 0.3 mean difference
Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study2015NCT01114360