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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed

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Atlas Graph Access Compounds Outcomes Proteins Interactions Papers Articles Pathways Processes Anatomy Cell types Organisms Materials Assessments

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Catalyst

The evidence graph for human biochemistry. Every edge carries its source, its study design, and a grade computed from both.

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Anatomy
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Materials
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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Reaction

MAM00213c+S-adenosyl-L-methionineMAM00212c+proton+CHEBI:16680

Left to right · Balance undeterminable · EC 2.1.1.354

Compartment: GO:0005829

Inferred

Reference data, not a finding. Evidence key

Catalysts

KMT2C&KMT2B
KMT2D&KMT2C
SETD1A
SUV39H1
DOT1L
NSD2
KMT5B
ASH1L
KMT2A
KMT5C
SETDB2
SETD1B
SETDB1
SETD7
NSD3
SUV39H2
NSD1
SETMAR
EHMT1
SETD2
KMT5A
SMYD3
EHMT2

Human-GEM MAR06976·2.0.1·CC BY 4.0Reference data