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Proteins/UNIPROT:Q8NET8
Non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. The channel pore can dilate to provide permeability to larger cations. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen)..
Function from UniProtKB (Q8NET8), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
13 statements
13 statements · 4 reference databases · Subject: TRPV3 · Sources: gene ontology, Hetionet, Reactome, Rhea
4 reactions
2 names
Resolves to: TRPV3
Transported by ANO9 or HTR3E or TMEM150C or CACNA1A or GRIN2D or P2RX6 or GRID2 or CACNA1G or GRIN3B or CACNA1F or TRPA1 or TRPM2 and 106 more alternatives
Reaction pageRight to leftBalanced
Rhea RHEA:29671CC BY 4.0Reference data
Transported by TMEM150C or TRPA1 or VDAC1 or GRIA1 or HTR3A or GRIA4 or CLDN10 or NIPAL4 or TMEM63B or NIPAL1 or NIPA1 or PKD1L3 and 17 more alternatives
Reaction pageDirection not assertedBalanced
Rhea RHEA:29827CC BY 4.0Reference data
Transported by ANO9 or HTR3E or TMEM150C or KCNK1 or KCNK3 or GRIN2D or GRID2 or KCNQ3 or KCNQ2 or GRIN3B or HCN1 or TRPA1 and 98 more alternatives
Reaction pageRight to leftBalanced
Rhea RHEA:34963CC BY 4.0Reference data