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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q96JJ7

TMX3

Protein·UNIPROT:Q96JJ7

Open in the graph

Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase. Acts as a regulator of endoplasmic reticulum-mitochondria contact sites via its ability to regulate redox signals..

Function from UniProtKB (Q96JJ7), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

7 statements

7 statements · 3 reference databases · Subject: TMX3 · Sources: Hetionet, Human-GEM, Reactome

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APP interacts with TMX3ProteinHetionet hetionet:interacts:351-54495Inferred only
UBC interacts with TMX3ProteinHetionet hetionet:interacts:54495-7316Inferred only
TMX3 participates in HemostasisPathwayReactome R-HSA-109582Inferred only
TMX3 participates in Platelet activation, signaling and aggregationPathwayReactome R-HSA-76002Inferred only
TMX3 participates in Platelet degranulationPathwayReactome R-HSA-114608Inferred only
TMX3 participates in Response to elevated platelet cytosolic Ca2+PathwayReactome R-HSA-76005Inferred only
CHEBI:16856 is a substrate of TMX3CompoundHuman-GEM MAR09806Inferred only

Reactions

1 reaction

2CHEBI:16856+MAM03169cglutathione disulfide+MAM03170c
Catalysed by PDIA5 or PDIA6 or PDIA4 or TMX3 or PDIA3 or P4HB
Reaction pageLeft to rightBalancedEC 5.3.4.1cytosol
Human-GEM MAR09806CC BY 4.0Reference data

Other names

4 names

Resolves to: TMX3

Also called: KIAA1830Thioredoxin domain-containing protein 10Thioredoxin-related transmembrane protein 3TXNDC10

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