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Proteins/UNIPROT:Q15005
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity)..
Function from UniProtKB (Q15005), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
41 statements
41 statements · 3 reference databases · Subject: SPCS2 · Sources: Hetionet, Reactome, WikiPathways
2 reactions
MAM00211c+waterprotein polypeptide chain+proton+N(6),N(6),N(6)-trimethyl-L-lysine
Catalysed by SPCS3 & SEC11A & SPCS2 & SEC11C & SPCS1
Reaction pageLeft to rightBalance undeterminableEC 3.4.21.89, 3.4.-.-cytosol
Human-GEM MAR06978CC BY 4.0Reference data
MAM00211r+waterprotein polypeptide chain+
4 names
Resolves to: SPCS2
Reaction pageLeft to rightBalance undeterminableEC 3.4.21.89, 3.4.-.-endoplasmic reticulum
Human-GEM MAR08029CC BY 4.0Reference data