Compound
N(6),N(6),N(6)-trimethyl-L-lysine
A zwitterionic form of N6,N6,N6-trimethyl-L-lysinium cation arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3
Definition from ChEBI (CHEBI:58100), read 2026-09-23. CC BY 4.0.
Structure
Loading the model…
- Class
- Organic compound, cation
- Formula
- C9H21N2O2
- Mass
- 189.279 g/mol
- Charge
- +1
- InChIKey
- MXNRLFUSFKVQSK-QMMMGPOBSA-O
- SMILES
- C[N+](C)(C)CCCC[C@H]([NH3+])C(=O)[O-]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Chemical structure
- (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine has the functional parent N(6),N(6),N(6)-trimethyl-L-lysineCompoundChEBI CHEBI:141499Inferred only
Statements
6 statements
6 statements · 2 reference databases · Subject: N(6),N(6),N(6)-trimethyl-L-lysine · Sources: Human-GEM, Rhea
- N(6),N(6),N(6)-trimethyl-L-lysine is converted to (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysineCompoundRhea RHEA:14181Inferred only
- (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine is converted to N(6),N(6),N(6)-trimethyl-L-lysineCompoundRhea RHEA:14181Inferred only
- N(6),N(6),N(6)-trimethyl-L-lysine is converted to 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine zwitterionCompoundHuman-GEM MAR06979Inferred only
- N(6),N(6),N(6)-trimethyl-L-lysine is a substrate of TMLHEProteinHuman-GEM MAR06979Inferred only
- N(6),N(6),N(6)-trimethyl-L-lysine is a substrate of TMLHEProteinRhea RHEA:14181Inferred only
- N(6),N(6),N(6)-trimethyl-L-lysine is transported by SLC25A45ProteinRhea RHEA:86419Inferred only
Reactions
8 reactions
MAM00211c+waterprotein polypeptide chain+proton+N(6),N(6),N(6)-trimethyl-L-lysine
Catalysed by SPCS3 & SEC11A & SPCS2 & SEC11C & SPCS1
Reaction pageLeft to rightBalance undeterminableEC 3.4.21.89, 3.4.-.-cytosol
Human-GEM MAR06978CC BY 4.0Reference data
2-oxoglutarate(2-)+N(6),N(6),N(6)-trimethyl-L-lysine+dioxygen3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine zwitterion+carbon dioxide+succinate(2-)
Catalysed by TMLHE
Reaction pageLeft to rightBalancedEC 1.14.11.8cytosol
Human-GEM MAR06979CC BY 4.0Reference data
MAM00211r+waterprotein polypeptide chain+proton+N(6),N(6),N(6)-trimethyl-L-lysine
Catalysed by SPCS3 & SEC11A & SPCS2 & SEC11C & SPCS1
Reaction pageLeft to rightBalance undeterminableEC 3.4.21.89, 3.4.-.-endoplasmic reticulum
Human-GEM MAR08029CC BY 4.0Reference data
N(6),N(6),N(6)-trimethyl-L-lysineN(6),N(6),N(6)-trimethyl-L-lysine
Reaction pageLeft to rightBalancedendoplasmic reticulum, cytosol
Human-GEM MAR08030CC BY 4.0Reference data
N(6),N(6),N(6)-trimethyl-L-lysine
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR10343CC BY 4.0Reference data
N(6),N(6),N(6)-trimethyl-L-lysineN(6),N(6),N(6)-trimethyl-L-lysine
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR10405CC BY 4.0Reference data
N(6),N(6),N(6)-trimethyl-L-lysine+2-oxoglutarate(2-)+dioxygen(3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine+succinate(2-)+carbon dioxide
Catalysed by TMLHE
Reaction pageDirection not assertedBalanced
Rhea RHEA:14181CC BY 4.0Reference data
N(6),N(6),N(6)-trimethyl-L-lysineN(6),N(6),N(6)-trimethyl-L-lysine
Transported by SLC25A45
Reaction pageDirection not assertedBalanced
Rhea RHEA:86419CC BY 4.0Reference data
Other names
1 name
Resolves to: N(6),N(6),N(6)-trimethyl-L-lysine
- Systematic name
- (2S)-2-azaniumyl-6-(trimethylazaniumyl)hexanoate