Proteins/UNIPROT:Q9BX66

SORBS1

ProteinUNIPROT:Q9BX66

Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity)..

Function from UniProtKB (Q9BX66), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

40 statements

40 statements · 4 reference databases · Subject: SORBS1 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

ADRA2C covaries with SORBS1ProteinHetionet hetionet:covaries:10580-152Inferred only
RRP7A covaries with SORBS1ProteinHetionet hetionet:covaries:10580-27341Inferred only
ABI1 interacts with SORBS1ProteinHetionet hetionet:interacts:10006-10580Inferred only
ABL1 interacts with SORBS1ProteinHetionet hetionet:interacts:10580-25Inferred only
ACTA1 interacts with SORBS1ProteinHetionet hetionet:interacts:10580-58Inferred only
ADAM15 interacts with SORBS1ProteinHetionet hetionet:interacts:10580-8751Inferred only
CBL interacts with SORBS1ProteinHetionet hetionet:interacts:10580-867Inferred only
CDK6 interacts with SORBS1ProteinHetionet hetionet:interacts:1021-10580Inferred only
DNM2 interacts with SORBS1ProteinHetionet hetionet:interacts:10580-1785Inferred only
EFNB1 interacts with SORBS1ProteinHetionet hetionet:interacts:10580-1947Inferred only
FLOT1 interacts with SORBS1ProteinHetionet hetionet:interacts:10211-10580Inferred only
INPPL1 interacts with SORBS1ProteinHetionet hetionet:interacts:10580-3636Inferred only

Show the remaining 28

INSM1 interacts with SORBS1ProteinHetionet hetionet:interacts:10580-3642Inferred only
INSR interacts with SORBS1ProteinHetionet hetionet:interacts:10580-3643Inferred only
MAP4K3 interacts with SORBS1ProteinHetionet hetionet:interacts:10580-8491Inferred only
PAK2 interacts with SORBS1ProteinHetionet hetionet:interacts:10580-5062Inferred only
PGR interacts with SORBS1ProteinHetionet hetionet:interacts:10580-5241Inferred only
SORBS1 interacts with PILRAProteinHetionet hetionet:interacts:10580-29992Inferred only
PTK2 interacts with SORBS1ProteinHetionet hetionet:interacts:10580-5747Inferred only
PXN interacts with SORBS1ProteinHetionet hetionet:interacts:10580-5829Inferred only
RPL4 interacts with SORBS1ProteinHetionet hetionet:interacts:10580-6124Inferred only
SORBS1 interacts with SEMA6AProteinHetionet hetionet:interacts:10580-57556Inferred only
SORBS1 interacts with SH2B2ProteinHetionet hetionet:interacts:10580-10603Inferred only
SLC10A3 interacts with SORBS1ProteinHetionet hetionet:interacts:10580-8273Inferred only
SMAD2 interacts with SORBS1ProteinHetionet hetionet:interacts:10580-4087Inferred only
VCL interacts with SORBS1ProteinHetionet hetionet:interacts:10580-7414Inferred only
SORBS1 participates in Insulin signalingPathwayWikiPathways WP481Inferred only
SORBS1 participates in Integrin mediated cell adhesionPathwayWikiPathways WP185Inferred only
SORBS1 participates in Muscle contractionPathwayReactome R-HSA-397014Inferred only
SORBS1 participates in PPAR signalingPathwayWikiPathways WP3942Inferred only
SORBS1 participates in Smooth Muscle ContractionPathwayReactome R-HSA-445355Inferred only
SORBS1 regulates positive regulation of D-glucose import across plasma membraneBiological processgene ontology Q9BX66|GO:0046326Inferred only
SORBS1 regulates positive regulation of glycogen biosynthetic processBiological processgene ontology Q9BX66|GO:0045725Inferred only
SORBS1 regulates positive regulation of insulin receptor signaling pathwayBiological processgene ontology Q9BX66|GO:0046628Inferred only
SORBS1 regulates positive regulation of lipid biosynthetic processBiological processgene ontology Q9BX66|GO:0046889Inferred only
SORBS1 regulates positive regulation of protein localization to plasma membraneBiological processgene ontology Q9BX66|GO:1903078Inferred only
DVL2 increases the expression of SORBS1ProteinHetionet hetionet:regulates:1856-10580Inferred only
JAG1 increases the expression of SORBS1ProteinHetionet hetionet:regulates:182-10580Inferred only
PMPCB increases the expression of SORBS1ProteinHetionet hetionet:regulates:9512-10580Inferred only
PNP decreases the expression of SORBS1ProteinHetionet hetionet:regulates:4860-10580Inferred only

Other names

8 names

Resolves to: SORBS1

Also called: c-Cbl-associated proteinCAPKIAA0894KIAA1296PonsinSH3 domain protein 5SH3D5SH3P12

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