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Proteins/UNIPROT:P54136
Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1..
Function from UniProtKB (P54136), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · substrate of
1 compound
1 compound.
0 reported routes1 assembled route
1 row
52 statements
52 statements · 6 reference databases · Subject: RARS1 · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
2 reactions
L-arginine+ATP+MAM03064cAMP+MAM02340c+diphosphate(3-)
Catalysed by RARS1
Reaction pageLeft to rightBalance undeterminableEC 6.1.1.19cytosol
Human-GEM MAR05132CC BY 4.0Reference data
CHEBI:78442+L-arginine+ATP(4-)CHEBI:78513+AMP+diphosphate(3-)
Catalysed by
3 names
Resolves to: RARS1
Reaction pageDirection not assertedBalanced
Rhea RHEA:20301CC BY 4.0Reference data