Proteins/UNIPROT:O43653

PSCA

ProteinUNIPROT:O43653

May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro..

May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs..

Function from UniProtKB (O43653), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

12 statements

12 statements · 3 reference databases · Subject: PSCA · Sources: gene ontology, Hetionet, Reactome

Order

PSCA covaries with SIAH3ProteinHetionet hetionet:covaries:283514-8000Inferred only
PSCA participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
PSCA participates in Post-translational modification: synthesis of GPI-anchored proteinsPathwayReactome R-HSA-163125Inferred only
PSCA participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
PSCA regulates negative regulation of ERK1 and ERK2 cascadeBiological processgene ontology O43653|GO:0070373Inferred only
PSCA regulates regulation of neurotransmitter receptor activityBiological processgene ontology O43653|GO:0099601Inferred only
BCKDHA decreases the expression of PSCAProteinHetionet hetionet:regulates:593-8000Inferred only
COQ8A decreases the expression of PSCAProteinHetionet hetionet:regulates:56997-8000Inferred only
DECR1 increases the expression of PSCAProteinHetionet hetionet:regulates:1666-8000Inferred only
GNPDA1 decreases the expression of PSCAProteinHetionet hetionet:regulates:10007-8000Inferred only
MAST2 decreases the expression of PSCAProteinHetionet hetionet:regulates:23139-8000Inferred only
NSDHL decreases the expression of PSCAProteinHetionet hetionet:regulates:50814-8000Inferred only

Other names

1 name

Resolves to: PSCA

Also called: Prostate stem cell antigen

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