Proteins/UNIPROT:Q3B726

POLR1F

ProteinUNIPROT:Q3B726

Component of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase which synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates. Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters..

Function from UniProtKB (Q3B726), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

15 statements

15 statements · 3 reference databases · Subject: POLR1F · Sources: Hetionet, Reactome, WikiPathways

Order

POLR1F covaries with ADAMTS1ProteinHetionet hetionet:covaries:221830-9510Inferred only
ARRB2 interacts with POLR1FProteinHetionet hetionet:interacts:221830-409Inferred only
PPP1CC interacts with POLR1FProteinHetionet hetionet:interacts:221830-5501Inferred only
POLR1F participates in 2q13 copy number variation syndromePathwayWikiPathways WP5222Inferred only
POLR1F participates in B-WICH complex positively regulates rRNA expressionPathwayReactome R-HSA-5250924Inferred only
POLR1F participates in Epigenetic regulation of gene expressionPathwayReactome R-HSA-212165Inferred only
POLR1F participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
POLR1F participates in Negative epigenetic regulation of rRNA expressionPathwayReactome R-HSA-5250941Inferred only
POLR1F participates in NoRC negatively regulates rRNA expressionPathwayReactome R-HSA-427413Inferred only
POLR1F participates in Positive epigenetic regulation of rRNA expressionPathwayReactome R-HSA-5250913Inferred only
POLR1F participates in Pyrimidine metabolismPathwayWikiPathways WP4022Inferred only
POLR1F participates in RNA Polymerase I Promoter EscapePathwayReactome R-HSA-73772Inferred only

Show the remaining 3

POLR1F participates in RNA Polymerase I TranscriptionPathwayReactome R-HSA-73864Inferred only
POLR1F participates in RNA Polymerase I Transcription InitiationPathwayReactome R-HSA-73762Inferred only
POLR1F participates in RNA Polymerase I Transcription TerminationPathwayReactome R-HSA-73863Inferred only

Other names

3 names

Resolves to: POLR1F

Also called: DNA-directed RNA polymerase I subunit FTwist neighbor proteinTWISTNB

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