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Proteins/UNIPROT:Q9UHI8
Metalloprotease which cleaves aggrecan, a cartilage proteoglycan, at the '1938-Glu-|-Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover (By similarity). Also cleaves COMP. Has angiogenic inhibitor activity. May play a critical role in follicular rupture (By similarity)..
Function from UniProtKB (Q9UHI8), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
31 statements
31 statements · 5 reference databases · Subject: ADAMTS1 · Sources: gene ontology, Hetionet, Reactome, UniProt, WikiPathways
6 names
Resolves to: ADAMTS1