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Proteins/UNIPROT:Q9HBY0
NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor, upon formation of a complex with CYBA/p22phox. Plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity (By similarity)..
Function from UniProtKB (Q9HBY0), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
13 statements
13 statements · 5 reference databases · Subject: NOX3 · Sources: Hetionet, Reactome, Rhea, UniProt, WikiPathways
1 reaction
NADPH(4-)+2dioxygen2superoxide+NADP(3-)+hydron
Catalysed by CYBB or NOX5 or NOX3 or NOX4 or NOX1
Reaction pageDirection not assertedBalanced
Rhea RHEA:63180CC BY 4.0Reference data
5 names
Resolves to: NOX3