Proteins/UNIPROT:Q96S06

LMF1

ProteinUNIPROT:Q96S06

Involved in the maturation of specific proteins in the endoplasmic reticulum. Required for maturation and transport of active lipoprotein lipase (LPL) through the secretory pathway. Each LMF1 molecule chaperones 50 or more molecules of LPL..

Function from UniProtKB (Q96S06), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

lipase deficiency, combined has a germline basis in LMF1DiseaseGenCC HGNC:14154|MONDO:0009527Inferred only

Statements

19 statements

19 statements · 3 reference databases · Subject: LMF1 · Sources: Hetionet, Reactome, WikiPathways

Order

LMF1 participates in Assembly of active LPL and LIPC lipase complexesPathwayReactome R-HSA-8963889Inferred only
LMF1 participates in Familial hyperlipidemia type 1PathwayWikiPathways WP5108Inferred only
LMF1 participates in Familial hyperlipidemia type 4PathwayWikiPathways WP5111Inferred only
LMF1 participates in Familial hyperlipidemia type 5PathwayWikiPathways WP5112Inferred only
LMF1 participates in Plasma lipoprotein assembly, remodeling, and clearancePathwayReactome R-HSA-174824Inferred only
LMF1 participates in Plasma lipoprotein remodelingPathwayReactome R-HSA-8963899Inferred only
LMF1 participates in Transport of small moleculesPathwayReactome R-HSA-382551Inferred only
CDKN1A decreases the expression of LMF1ProteinHetionet hetionet:regulates:1026-64788Inferred only
DAXX increases the expression of LMF1ProteinHetionet hetionet:regulates:1616-64788Inferred only
DHPS increases the expression of LMF1ProteinHetionet hetionet:regulates:1725-64788Inferred only
DMTF1 decreases the expression of LMF1ProteinHetionet hetionet:regulates:9988-64788Inferred only
ERCC1 decreases the expression of LMF1ProteinHetionet hetionet:regulates:2067-64788Inferred only

Show the remaining 7

ERGIC2 increases the expression of LMF1ProteinHetionet hetionet:regulates:51290-64788Inferred only
GUK1 increases the expression of LMF1ProteinHetionet hetionet:regulates:2987-64788Inferred only
IGF2 increases the expression of LMF1ProteinHetionet hetionet:regulates:3481-64788Inferred only
MBNL1 increases the expression of LMF1ProteinHetionet hetionet:regulates:4154-64788Inferred only
NME1 increases the expression of LMF1ProteinHetionet hetionet:regulates:4830-64788Inferred only
STAMBP increases the expression of LMF1ProteinHetionet hetionet:regulates:10617-64788Inferred only
TP53 decreases the expression of LMF1ProteinHetionet hetionet:regulates:7157-64788Inferred only

Other names

4 names

Resolves to: LMF1

Also called: C16orf26Lipase maturation factor 1TMEM112Transmembrane protein 112

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