Proteins/UNIPROT:Q9NS61

KCNIP2

ProteinUNIPROT:Q9NS61

Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. Involved in KCND2 and KCND3 trafficking to the cell surface. May be required for the expression of I(To) currents in the heart (By similarity)..

Function from UniProtKB (Q9NS61), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

21 statements

21 statements · 3 reference databases · Subject: KCNIP2 · Sources: gene ontology, Hetionet, Reactome

Order

ACTG1 covaries with KCNIP2ProteinHetionet hetionet:covaries:30819-71Inferred only
KCNIP2 covaries with BRDTProteinHetionet hetionet:covaries:30819-676Inferred only
CCN2 covaries with KCNIP2ProteinHetionet hetionet:covaries:1490-30819Inferred only
DDX23 covaries with KCNIP2ProteinHetionet hetionet:covaries:30819-9416Inferred only
IGFBP7 covaries with KCNIP2ProteinHetionet hetionet:covaries:30819-3490Inferred only
RPL38 covaries with KCNIP2ProteinHetionet hetionet:covaries:30819-6169Inferred only
SESTD1 covaries with KCNIP2ProteinHetionet hetionet:covaries:30819-91404Inferred only
TAS2R9 covaries with KCNIP2ProteinHetionet hetionet:covaries:30819-50835Inferred only
KCND2 interacts with KCNIP2ProteinHetionet hetionet:interacts:30819-3751Inferred only
KCND3 interacts with KCNIP2ProteinHetionet hetionet:interacts:30819-3752Inferred only
KCNIP2 interacts with KCNIP1ProteinHetionet hetionet:interacts:30819-30820Inferred only
KCNIP2 interacts with KCNIP4ProteinHetionet hetionet:interacts:30819-80333Inferred only

Show the remaining 9

KCNIP2 participates in Cardiac conductionPathwayReactome R-HSA-5576891Inferred only
KCNIP2 participates in Muscle contractionPathwayReactome R-HSA-397014Inferred only
KCNIP2 participates in Phase 1 - inactivation of fast Na+ channelsPathwayReactome R-HSA-5576894Inferred only
KCNIP2 regulates positive regulation of potassium ion export across plasma membraneBiological processgene ontology Q9NS61|GO:1903766Inferred only
KCNIP2 regulates regulation of heart contractionBiological processgene ontology Q9NS61|GO:0008016Inferred only
KCNIP2 regulates regulation of membrane repolarizationBiological processgene ontology Q9NS61|GO:0060306Inferred only
KCNIP2 regulates regulation of potassium ion export across plasma membraneBiological processgene ontology Q9NS61|GO:1903764Inferred only
KCNIP2 regulates regulation of potassium ion transmembrane transportBiological processgene ontology Q9NS61|GO:1901379Inferred only
KCNIP2 regulates regulation of signal transductionBiological processgene ontology Q9NS61|GO:0009966Inferred only

Other names

4 names

Resolves to: KCNIP2

Also called: Cardiac voltage-gated potassium channel modulatory subunitKCHIP2Kv channel-interacting protein 2Potassium channel-interacting protein 2

← Every protein Find it in the graph →