Proteins/UNIPROT:Q86VW0

SESTD1

ProteinUNIPROT:Q86VW0

May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1..

Function from UniProtKB (Q86VW0), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

8 statements

8 statements · 2 reference databases · Subject: SESTD1 · Sources: gene ontology, Hetionet

Order

SESTD1 covaries with BTBD2ProteinHetionet hetionet:covaries:55643-91404Inferred only
SESTD1 covaries with CA11ProteinHetionet hetionet:covaries:770-91404Inferred only
HOXC12 covaries with SESTD1ProteinHetionet hetionet:covaries:3228-91404Inferred only
SESTD1 covaries with KCNIP2ProteinHetionet hetionet:covaries:30819-91404Inferred only
MAGEE2 covaries with SESTD1ProteinHetionet hetionet:covaries:139599-91404Inferred only
NUDT10 covaries with SESTD1ProteinHetionet hetionet:covaries:170685-91404Inferred only
SESTD1 covaries with TMEM238ProteinHetionet hetionet:covaries:388564-91404Inferred only
SESTD1 regulates negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channelBiological processgene ontology Q86VW0|GO:1904878Inferred only

Other names

3 names

Resolves to: SESTD1

Also called: Huntingtin-interacting protein-like proteinProtein SoloSOLO

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