Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Proteins/UNIPROT:Q70UQ0

IKBIP

Protein·UNIPROT:Q70UQ0

Open in the graph

Target of p53/TP53 with pro-apoptotic function..

Function from UniProtKB (Q70UQ0), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

32 statements

32 statements · 2 reference databases · Subject: IKBIP · Sources: Hetionet, Reactome

Search this listOrder

APP interacts with IKBIPProteinHetionet hetionet:interacts:121457-351Inferred only
FBXO6 interacts with IKBIPProteinHetionet hetionet:interacts:121457-26270Inferred only
IKBKB interacts with IKBIPProteinHetionet hetionet:interacts:121457-3551Inferred only
UBC interacts with IKBIPProteinHetionet hetionet:interacts:121457-7316Inferred only
IKBIP participates in Cytokine Signaling in Immune systemPathwayReactome R-HSA-1280215Inferred only
IKBIP participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
IKBIP participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
IKBIP participates in Interleukin-1 family signalingPathwayReactome R-HSA-446652Inferred only
IKBIP participates in Interleukin-1 signalingPathwayReactome R-HSA-9020702Inferred only
IKBIP participates in MyD88 cascade initiated on plasma membranePathwayReactome R-HSA-975871Inferred only
IKBIP participates in MyD88 dependent cascade initiated on endosomePathwayReactome R-HSA-975155Inferred only
IKBIP participates in MyD88-independent TLR4 cascadePathwayReactome R-HSA-166166Inferred only

Show the remaining 20

IKBIP participates in MyD88:MAL(TIRAP) cascade initiated on plasma membranePathwayReactome R-HSA-166058Inferred only
IKBIP participates in Regulation of NF-kappa B signalingPathwayReactome R-HSA-9758274Inferred only
IKBIP participates in Signaling by InterleukinsPathwayReactome R-HSA-449147Inferred only
IKBIP participates in TAK1-dependent IKK and NF-kappa-B activationPathwayReactome R-HSA-445989Inferred only
IKBIP participates in Toll Like Receptor 10 (TLR10) CascadePathwayReactome R-HSA-168142Inferred only
IKBIP participates in Toll Like Receptor 2 (TLR2) CascadePathwayReactome R-HSA-181438Inferred only
IKBIP participates in Toll Like Receptor 3 (TLR3) CascadePathwayReactome R-HSA-168164Inferred only
IKBIP participates in Toll Like Receptor 4 (TLR4) CascadePathwayReactome R-HSA-166016Inferred only
IKBIP participates in Toll Like Receptor 5 (TLR5) CascadePathwayReactome R-HSA-168176Inferred only
IKBIP participates in Toll Like Receptor 7/8 (TLR7/8) CascadePathwayReactome R-HSA-168181Inferred only
IKBIP participates in Toll Like Receptor 9 (TLR9) CascadePathwayReactome R-HSA-168138Inferred only
IKBIP participates in Toll Like Receptor TLR1:TLR2 CascadePathwayReactome R-HSA-168179Inferred only
IKBIP participates in Toll Like Receptor TLR6:TLR2 CascadePathwayReactome R-HSA-168188Inferred only
IKBIP participates in Toll-like Receptor CascadesPathwayReactome R-HSA-168898Inferred only
IKBIP participates in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activationPathwayReactome R-HSA-975138Inferred only
IKBIP participates in TRIF (TICAM1)-mediated TLR4 signalingPathwayReactome R-HSA-937061Inferred only
IKBIP decreases the expression of GJA1ProteinHetionet hetionet:regulates:121457-2697Inferred only
IKBIP increases the expression of MAGEA6ProteinHetionet hetionet:regulates:121457-4105Inferred only
IKBIP increases the expression of MALProteinHetionet hetionet:regulates:121457-4118Inferred only
IKBIP increases the expression of PLS1ProteinHetionet hetionet:regulates:121457-5357Inferred only

Other names

4 names

Resolves to: IKBIP

Also called: I kappa-B kinase-interacting proteinIKBKB-interacting proteinIKIPIKK-interacting protein

← Every protein Find it in the graph →