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Proteins/UNIPROT:Q7L7L0
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Function from UniProtKB (Q7L7L0), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
41 statements
41 statements · 2 reference databases · Subject: H2AC25 · Sources: Hetionet, Reactome
4 names
Resolves to: H2AC25