Proteins/UNIPROT:P56279

TCL1A

ProteinUNIPROT:P56279

Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival..

Function from UniProtKB (P56279), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

15 statements

15 statements · 2 reference databases · Subject: TCL1A · Sources: Hetionet, WikiPathways

Order

CRTC1 covaries with TCL1AProteinHetionet hetionet:covaries:23373-8115Inferred only
SULT1B1 covaries with TCL1AProteinHetionet hetionet:covaries:27284-8115Inferred only
AKT1 interacts with TCL1AProteinHetionet hetionet:interacts:207-8115Inferred only
AKT2 interacts with TCL1AProteinHetionet hetionet:interacts:208-8115Inferred only
TCL1A interacts with AKT3ProteinHetionet hetionet:interacts:10000-8115Inferred only
ATM interacts with TCL1AProteinHetionet hetionet:interacts:472-8115Inferred only
TCL1A interacts with CALCOCO2ProteinHetionet hetionet:interacts:10241-8115Inferred only
EP300 interacts with TCL1AProteinHetionet hetionet:interacts:2033-8115Inferred only
TCL1A interacts with H2AC25ProteinHetionet hetionet:interacts:8115-92815Inferred only
JUN interacts with TCL1AProteinHetionet hetionet:interacts:3725-8115Inferred only
JUNB interacts with TCL1AProteinHetionet hetionet:interacts:3726-8115Inferred only
TCL1A participates in Focal adhesion PI3K Akt mTOR signalingPathwayWikiPathways WP3932Inferred only

Show the remaining 3

TCL1A participates in miR targeted genes in lymphocytesPathwayWikiPathways WP2004Inferred only
TCL1A participates in PI3K Akt signalingPathwayWikiPathways WP4172Inferred only
ABL1 decreases the expression of TCL1AProteinHetionet hetionet:regulates:25-8115Inferred only

Other names

5 names

Resolves to: TCL1A

Also called: Oncogene TCL-1Oncogene TCL1p14 TCL1Protein p14 TCL1TCL1

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