Proteins/UNIPROT:P30711

GSTT1

ProteinUNIPROT:P30711Glutathione S-transferase theta-1

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide..

Function from UniProtKB (P30711), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

28 statements

28 statements · 3 reference databases · Subject: GSTT1 · Sources: Hetionet, Reactome, Rhea

Order

GSTT1 covaries with SMNDC1ProteinHetionet hetionet:covaries:10285-2952Inferred only
GSTT1 covaries with ZNF580ProteinHetionet hetionet:covaries:2952-51157Inferred only
glutathione is metabolised by GSTT1CompoundRhea RHEA:16437Inferred only
RX is metabolised by GSTT1CompoundRhea RHEA:16437Inferred only
GSTT1 participates in Biological oxidationsPathwayReactome R-HSA-211859Inferred only
GSTT1 participates in Drug ADMEPathwayReactome R-HSA-9748784Inferred only
GSTT1 participates in Glutathione conjugationPathwayReactome R-HSA-156590Inferred only
GSTT1 participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
GSTT1 participates in Paracetamol ADMEPathwayReactome R-HSA-9753281Inferred only
GSTT1 participates in Phase II - Conjugation of compoundsPathwayReactome R-HSA-156580Inferred only
GSTT1 decreases the expression of CCDC86ProteinHetionet hetionet:regulates:2952-79080Inferred only
GSTT1 increases the expression of CCP110ProteinHetionet hetionet:regulates:2952-9738Inferred only

Show the remaining 16

GSTT1 decreases the expression of DKK3ProteinHetionet hetionet:regulates:2952-27122Inferred only
GSTT1 decreases the expression of FOXO4ProteinHetionet hetionet:regulates:2952-4303Inferred only
GSTT1 decreases the expression of GOLT1BProteinHetionet hetionet:regulates:2952-51026Inferred only
GSTT1 decreases the expression of HADHProteinHetionet hetionet:regulates:2952-3033Inferred only
HDAC3 decreases the expression of GSTT1ProteinHetionet hetionet:regulates:8841-2952Inferred only
HSPA5 decreases the expression of GSTT1ProteinHetionet hetionet:regulates:3309-2952Inferred only
GSTT1 decreases the expression of IFRD2ProteinHetionet hetionet:regulates:2952-7866Inferred only
GSTT1 increases the expression of MLLT11ProteinHetionet hetionet:regulates:2952-10962Inferred only
GSTT1 decreases the expression of MRPS16ProteinHetionet hetionet:regulates:2952-51021Inferred only
GSTT1 decreases the expression of MTFR1ProteinHetionet hetionet:regulates:2952-9650Inferred only
GSTT1 decreases the expression of PIN1ProteinHetionet hetionet:regulates:2952-5300Inferred only
GSTT1 increases the expression of SELLProteinHetionet hetionet:regulates:2952-6402Inferred only
GSTT1 decreases the expression of TP53BP2ProteinHetionet hetionet:regulates:2952-7159Inferred only
GSTT1 decreases the expression of TXLNAProteinHetionet hetionet:regulates:2952-200081Inferred only
GSTT1 decreases the expression of VAT1ProteinHetionet hetionet:regulates:2952-10493Inferred only
GSTT1 decreases the expression of ZFPL1ProteinHetionet hetionet:regulates:2952-7542Inferred only

Reactions

1 reaction

RX+glutathionean S-substituted glutathione+a halide anion+hydron
Catalysed by GSTT4 or GSTA4 or GSTZ1 or LANCL1 or HPGDS or GSTA1 or GSTA2 or GSTP1 or GSTM1 or GSTT2 or GSTT2B or MGST1 and 11 more alternatives

Other names

2 names

Resolves to: GSTT1

Also called: Glutathione transferase T1-1GST class-theta-1

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