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Proteins/UNIPROT:Q9NQX3
Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Acts as a major instructive molecule at inhibitory synapses, where it also clusters GABA type A receptors..
Also has a catalytic activity and catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released..
Function from UniProtKB (Q9NQX3), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
80 statements
80 statements · 8 reference databases · Subject: GPHN · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
3 reactions
ATP+proton+molybdopterinadenylyl-molybdopterin+diphosphate(3-)
Catalysed by GPHN
Reaction pageLeft to rightBalancedEC 2.7.7.75cytosol
Human-GEM MAR07147CC BY 4.0Reference data
molybdopterin+ATP(4-)+hydronadenylyl-molybdopterin+diphosphate(3-)
Catalysed by GPHN
8 names
Resolves to: GPHN
Rhea RHEA:31331CC BY 4.0Reference data
adenylyl-molybdopterin+molybdateMo-molybdopterin+AMP+hydron
Catalysed by GPHN
Reaction pageLeft to rightBalanced
Rhea RHEA:35047CC BY 4.0Reference data