Pathway
Histidine catabolism
The major pathway of histidine catabolism, annotated here, proceeds in four steps to yield glutamate and, in the process, convert one molecule of tetrahydrofolate to 5-formiminotetrahydrofolate. Histidine can also be decarboxylated to form histamine. Histidine can also be used to form carnosine (beta-alanyl-L-histidine), an abundant dipeptide in skeletal muscle and brain of most vertebrates.
REACT:R-HSA-70921Reactome
What the reference databases state
Statements
9 statements
9 statements · 1 reference database · Subject: Histidine catabolism · Sources: Reactome
- AMDHD1 participates in Histidine catabolismProteinReactome R-HSA-70921Inferred only
- AOC1 participates in Histidine catabolismProteinReactome R-HSA-70921Inferred only
- CARNMT1 participates in Histidine catabolismProteinReactome R-HSA-70921Inferred only
- CARNS1 participates in Histidine catabolismProteinReactome R-HSA-70921Inferred only
- FTCD participates in Histidine catabolismProteinReactome R-HSA-70921Inferred only
- HAL participates in Histidine catabolismProteinReactome R-HSA-70921Inferred only
- HDC participates in Histidine catabolismProteinReactome R-HSA-70921Inferred only
- HNMT participates in Histidine catabolismProteinReactome R-HSA-70921Inferred only
- UROC1 participates in Histidine catabolismProteinReactome R-HSA-70921Inferred only