Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Proteins/UNIPROT:P01215

CGA

Protein·UNIPROT:P01215

Open in the graph

Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways..

Function from UniProtKB (P01215), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

51 statements

51 statements · 4 reference databases · Subject: CGA · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Search this listOrder

CGA covaries with POLRMTProteinHetionet hetionet:covaries:1081-5442Inferred only
CGA interacts with CGB3; CGB5; CGB8ProteinHetionet hetionet:interacts:1081-93659Inferred only
CGA interacts with CGB3; CGB5; CGB8ProteinHetionet hetionet:interacts:1081-1082Inferred only
CGA interacts with CGB3; CGB5; CGB8ProteinHetionet hetionet:interacts:1081-94115Inferred only
CGA interacts with FSHBProteinHetionet hetionet:interacts:1081-2488Inferred only
CGA interacts with FSHRProteinHetionet hetionet:interacts:1081-2492Inferred only
CGA interacts with LHBProteinHetionet hetionet:interacts:1081-3972Inferred only
CGA interacts with LHCGRProteinHetionet hetionet:interacts:1081-3973Inferred only
CGA interacts with PTNProteinHetionet hetionet:interacts:1081-5764Inferred only
CGA interacts with PTPN12ProteinHetionet hetionet:interacts:1081-5782Inferred only
CGA interacts with TSHBProteinHetionet hetionet:interacts:1081-7252Inferred only
CGA participates in Androgen biosynthesisPathwayReactome R-HSA-193048Inferred only

Show the remaining 39

CGA participates in Asparagine N-linked glycosylationPathwayReactome R-HSA-446203Inferred only
CGA participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
CGA participates in Follicle stimulating hormone FSH signalingPathwayWikiPathways WP2035Inferred only
CGA participates in G alpha (s) signalling eventsPathwayReactome R-HSA-418555Inferred only
CGA participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
CGA participates in Generic Transcription PathwayPathwayReactome R-HSA-212436Inferred only
CGA participates in Glycoprotein hormonesPathwayReactome R-HSA-209822Inferred only
CGA participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
CGA participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
CGA participates in Hormone ligand-binding receptorsPathwayReactome R-HSA-375281Inferred only
CGA participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
CGA participates in Metabolism of amine-derived hormonesPathwayReactome R-HSA-209776Inferred only
CGA participates in Metabolism of amino acids and derivativesPathwayReactome R-HSA-71291Inferred only
CGA participates in Metabolism of lipidsPathwayReactome R-HSA-556833Inferred only
CGA participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
CGA participates in Metabolism of steroid hormonesPathwayReactome R-HSA-196071Inferred only
CGA participates in Metabolism of steroidsPathwayReactome R-HSA-8957322Inferred only
CGA participates in Mineralocorticoid biosynthesisPathwayReactome R-HSA-193993Inferred only
CGA participates in N-glycan antennae elongation in the medial/trans-GolgiPathwayReactome R-HSA-975576Inferred only
CGA participates in Orexin receptor pathwayPathwayWikiPathways WP5094Inferred only
CGA participates in Peptide hormone biosynthesisPathwayReactome R-HSA-209952Inferred only
CGA participates in Peptide hormone metabolismPathwayReactome R-HSA-2980736Inferred only
CGA participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
CGA participates in Prader Willi and Angelman syndromePathwayWikiPathways WP3998Inferred only
CGA participates in Reactions specific to the complex N-glycan synthesis pathwayPathwayReactome R-HSA-975578Inferred only
CGA participates in RNA Polymerase II TranscriptionPathwayReactome R-HSA-73857Inferred only
CGA participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
CGA participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
CGA participates in TFAP2 (AP-2) family regulates transcription of growth factors and their receptorsPathwayReactome R-HSA-8866910Inferred only
CGA participates in Thyroid stimulating hormone TSH signalingPathwayWikiPathways WP2032Inferred only
CGA participates in Thyroxine biosynthesisPathwayReactome R-HSA-209968Inferred only
CGA participates in Thyroxine thyroid hormone productionPathwayWikiPathways WP1981Inferred only
CGA participates in Transcriptional regulation by the AP-2 (TFAP2) family of transcription factorsPathwayReactome R-HSA-8864260Inferred only
CGA participates in Transport to the Golgi and subsequent modificationPathwayReactome R-HSA-948021Inferred only
CGA regulates positive regulation of cell migrationBiological processgene ontology P01215|GO:0030335Inferred only
CGA regulates positive regulation of cell population proliferationBiological processgene ontology P01215|GO:0008284Inferred only
CGA regulates positive regulation of steroid biosynthetic processBiological processgene ontology P01215|GO:0010893Inferred only
CGA regulates positive regulation of transcription by RNA polymerase IIBiological processgene ontology P01215|GO:0045944Inferred only
CGA regulates regulation of signaling receptor activityBiological processgene ontology P01215|GO:0010469Inferred only

Other names

13 names

Resolves to: CGA

Also called: Anterior pituitary glycoprotein hormones common subunit alphaCG-alphaChoriogonadotropin alpha chainChorionic gonadotrophin subunit alphaFollicle-stimulating hormone alpha chainFollitropin alpha chainFSH-alphaLSH-alphaLuteinizing hormone alpha chainLutropin alpha chainThyroid-stimulating hormone alpha chainThyrotropin alpha chainTSH-alpha

← Every protein Find it in the graph →