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Proteins/UNIPROT:Q13698
Pore-forming, alpha-1S subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle via their interaction with RYR1, which triggers Ca(2+) release from the sarcoplasmic reticulum and ultimately results in muscle contraction. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group..
Function from UniProtKB (Q13698), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · transported by
1 compound
1 compound.
0 reported routes1 assembled route
5 rows
27 statements
27 statements · 5 reference databases · Subject: CACNA1S · Sources: gene ontology, Hetionet, Reactome, Rhea, WikiPathways
1 reaction
5 names
Resolves to: CACNA1S