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Proteins/UNIPROT:Q16720
ATP-driven Ca(2+) ion pump involved in the maintenance of basal intracellular Ca(2+) levels at the presynaptic terminals. Uses ATP as an energy source to transport cytosolic Ca(2+) ions across the plasma membrane to the extracellular compartment. May counter-transport protons, but the mechanism and the stoichiometry of this Ca(2+)/H(+) exchange remains to be established (By similarity)..
Function from UniProtKB (Q16720), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
18 statements
18 statements · 6 reference databases · Subject: ATP2B3 · Sources: gene ontology, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
3 reactions
ATP+Ca(2+)+waterADP+Ca(2+)+proton+phosphate(3-)
Transported by ATP2B4 or ATP2B3 or ATP2B1 or ATP2B2
Reaction pageLeft to rightBalancedEC 7.1.2.1cytosol, extracellular space
Human-GEM MAR00119CC BY 4.0Reference data
3 names
Resolves to: ATP2B3
Transported by ATP2C1 or ATP2B4 or ATP2C2 or ATP2B3 or ATP2B1 or ATP2A3 or ATP2B2 or ATP2A2 or ATP2A1
Reaction pageLeft to rightBalancedEC 7.2.2.10cytosol, extracellular space
Human-GEM MAR07629CC BY 4.0Reference data