Pathway
Conjugation of carboxylic acids
Xenobiotics and endogenous compounds containing carboxylate groups can be activated with coenzyme A to produce acyl-CoA thioesters and then conjugated with the amino groups of glycine or glutamine to form amide-linked conjugates. Clinically important substrates include benzoic acid, phenylacetic acid, and salicylic acid.
REACT:R-HSA-159424Reactome
What the reference databases state
Statements
9 statements
9 statements · 1 reference database · Subject: Conjugation of carboxylic acids · Sources: Reactome
- ACSM1 participates in Conjugation of carboxylic acidsProteinReactome R-HSA-159424Inferred only
- ACSM2A participates in Conjugation of carboxylic acidsProteinReactome R-HSA-159424Inferred only
- ACSM2B participates in Conjugation of carboxylic acidsProteinReactome R-HSA-159424Inferred only
- ACSM4 participates in Conjugation of carboxylic acidsProteinReactome R-HSA-159424Inferred only
- ACSM5 participates in Conjugation of carboxylic acidsProteinReactome R-HSA-159424Inferred only
- GLYAT participates in Conjugation of carboxylic acidsProteinReactome R-HSA-159424Inferred only
- GLYATL1 participates in Conjugation of carboxylic acidsProteinReactome R-HSA-159424Inferred only
- GLYATL2 participates in Conjugation of carboxylic acidsProteinReactome R-HSA-159424Inferred only
- GLYATL3 participates in Conjugation of carboxylic acidsProteinReactome R-HSA-159424Inferred only