Endpoint
Colorectal adenoma recurrence after polypectomy
CAT:outcome/colorectal-adenoma-recurrencereported in proportion1 finding from 1 compound
What moved it
How to read these marks1 finding from 1 compound, best grade first.
| Compound | Direction | Findings | Best grade |
|---|---|---|---|
| berberine | down | 1 | Grade C, Suggestive. Weak human evidence, or strong evidence in a mismatched population. |
Reported to move it
1 finding
berberine — decreases
SuggestiveGrade C, Suggestive. Weak human evidence, or strong evidence in a mismatched population.Finding“Sensitivity analyses also demonstrated the same trend: patients in the berberine group had lower risk of colorectal adenoma recurrence (adjusted HR, 0.62; 95% CI: 0.49–0.79; p < 0.001) (Table S2).”
Quoted verbatim from Berberine for preventing colorectal adenoma recurrence and neoplasm occurrence: 6-Year follow-up of a randomized clinical trial.. - Study
- cohort
- Population
- Patients with resected colorectal adenoma from the CBAR trial, extended 6-year post-treatment follow-up (CBAR-FE study); sensitivity-analysis estimate
Effect 0.62 hazard ratio, 95% CI 0.49 to 0.79
Berberine for preventing colorectal adenoma recurrence and neoplasm occurrence: 6-Year follow-up of a randomized clinical trial.2025PMID:40795846
How it is measured
Recurrence of colorectal adenoma detected at surveillance colonoscopy following prior polypectomy, ascertained at the protocol's stated follow-up interval (commonly 1 or 2 years).
The method is part of the endpoint’s identity: two studies that measured the same word differently are held as separate endpoints.
Sources cited
1 paper
The 1 finding about colorectal adenoma recurrence after polypectomy on this page come from 1 paper, newest first. The count beside each opens the first finding drawn from it.