Papers/PMID:20685491
Supplemental calcium in the chemoprevention of colorectal cancer: a systematic review and meta-analysis.
Clinical therapeutics2010The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
Ca(2+) — decreases colorectal adenoma recurrence after polypectomy
Evidence strength: very limited.Findingreplicated ×1“Meta-analysis of 3 trials in individuals with a history of adenomas showed a statistically significant reduction in the RR for adenoma recurrence (RR = 0.80 [95% CI, 0.69-0.94], P = 0.006) for those receiving calcium 1200 to 2000 mg/d, but no effect was seen in advanced adenoma (RR = 0.77 [95% CI, 0.501.17], P = NS).”
Quoted verbatim from Supplemental calcium in the chemoprevention of colorectal cancer: a systematic review and meta-analysis.. - Study
- meta-analysis
- Dose
- calcium 1200 to 2000 mg/d
- Population
- Individuals with a history of colorectal adenomas, three pooled trials versus placebo
Effect 0.8 risk ratio, 95% CI 0.69 to 0.94
Supplemental calcium in the chemoprevention of colorectal cancer: a systematic review and meta-analysis.2010PMID:2068549110.1016/j.clinthera.2010.04.024Permalink