Papers/PMID:40795846
Berberine for preventing colorectal adenoma recurrence and neoplasm occurrence: 6-Year follow-up of a randomized clinical trial.
Cell reports. Medicine2025The record
1 finding drawn from this paper, on 1 compound across 1 endpoint.
What it reported
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1 finding
berberine — decreases colorectal adenoma recurrence after polypectomy
SuggestiveGrade C, Suggestive. Weak human evidence, or strong evidence in a mismatched population.Finding“Sensitivity analyses also demonstrated the same trend: patients in the berberine group had lower risk of colorectal adenoma recurrence (adjusted HR, 0.62; 95% CI: 0.49–0.79; p < 0.001) (Table S2).”
Quoted verbatim from Berberine for preventing colorectal adenoma recurrence and neoplasm occurrence: 6-Year follow-up of a randomized clinical trial.. - Study
- cohort
- Population
- Patients with resected colorectal adenoma from the CBAR trial, extended 6-year post-treatment follow-up (CBAR-FE study); sensitivity-analysis estimate
Effect 0.62 hazard ratio, 95% CI 0.49 to 0.79
Berberine for preventing colorectal adenoma recurrence and neoplasm occurrence: 6-Year follow-up of a randomized clinical trial.2025PMID:40795846