PapersPMID:40795846
Berberine for preventing colorectal adenoma recurrence and neoplasm occurrence: 6-Year follow-up of a randomized clinical trial.
- 01 · finding
- 1
- 02 · compound
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- 03 · endpoint
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- 04 · null
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What it reported
How to read these marksWhat moved
1 finding
berberine — decreases colorectal adenoma recurrence after polypectomy
Evidence strength: limited.Finding“Sensitivity analyses also demonstrated the same trend: patients in the berberine group had lower risk of colorectal adenoma recurrence (adjusted HR, 0.62; 95% CI: 0.49–0.79; p < 0.001) (Table S2).”
Quoted verbatim from Berberine for preventing colorectal adenoma recurrence and neoplasm occurrence: 6-Year follow-up of a randomized clinical trial.. - Study
- cohort
- Population
- Patients with resected colorectal adenoma from the CBAR trial, extended 6-year post-treatment follow-up (CBAR-FE study); sensitivity-analysis estimate
Effect 0.62 hazard ratio, 95% CI 0.49 to 0.79
Berberine for preventing colorectal adenoma recurrence and neoplasm occurrence: 6-Year follow-up of a randomized clinical trial.2025PMID:4079584610.1016/j.xcrm.2025.102293Permalink
Study record
Read under: berberine
- Design, as each reading recorded it
- cohort study / randomised controlled trial
- Species
- human
- Population
- adults post-polypectomy, extended 6-year follow-up of a completed 2-year randomized berberine colorectal-adenoma-prevention trial (CBAR)
- Participants
- 648
- Comparator
- not stated in the paper / placebo
- Duration
- not recorded
- Endpoints
- 4
- Record
- extracted
- Readings recorded
- 2