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Reference

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A reference for what the literature reports. Not medical advice.

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genistein

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

11 compounds within 3 steps: 1 in 1, 2 in 2, 8 in 3

Does it reach a compound?

One step

genistein 7-O-beta-D-glucosideReach from here →
1. genistein + UDP-alpha-D-glucose = genistein 7-O-beta-D-glucoside + UDP + H(+)
Catalysed by UGT3A2, UGT3A1

Two steps

beta-D-glucoseReach from here →
1. genistein + UDP-alpha-D-glucose = genistein 7-O-beta-D-glucoside + UDP + H(+)
2. genistein 7-O-beta-D-glucoside + H2O = genistein + beta-D-glucose
Catalysed by UGT3A2, UGT3A1, LCT
UDP-alpha-D-glucoseReach from here →
1. genistein + UDP-alpha-D-glucose = genistein 7-O-beta-D-glucoside + UDP + H(+)
2. genistein + UDP-alpha-D-glucose = genistein 7-O-beta-D-glucoside + UDP + H(+)
Catalysed by UGT3A2, UGT3A1

Three steps

alpha,alpha-trehaloseReach from here →
Catalysed by UGT3A2, UGT3A1, LCT, TREH
alpha-D-glucoseReach from here →
Catalysed by

a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enineReach from here →

genistein + UDP-alpha-D-glucose = genistein 7-O-beta-D-glucoside + UDP + H(+)
genistein + UDP-alpha-D-glucose = genistein 7-O-beta-D-glucoside + UDP + H(+)
an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)

Catalysed by UGT3A2, UGT3A1, UGCG

(2S)-naringenin 7-O-beta-D-glucosideReach from here →

genistein + UDP-alpha-D-glucose = genistein 7-O-beta-D-glucoside + UDP + H(+)
genistein + UDP-alpha-D-glucose = genistein 7-O-beta-D-glucoside + UDP + H(+)
(2S)-naringenin + UDP-alpha-D-glucose = (2S)-naringenin 7-O-beta-D-glucoside + UDP + H(+)

Catalysed by UGT3A2, UGT3A1

D-glucoseReach from here →

genistein + UDP-alpha-D-glucose = genistein 7-O-beta-D-glucoside + UDP + H(+)
genistein 7-O-beta-D-glucoside + H2O = genistein + beta-D-glucose
D-glucose 1-epimerase

Catalysed by UGT3A2, UGT3A1, LCT, GALMcytosol

daidzein 7-O-beta-D-glucosideReach from here →

genistein + UDP-alpha-D-glucose = genistein 7-O-beta-D-glucoside + UDP + H(+)
genistein + UDP-alpha-D-glucose = genistein 7-O-beta-D-glucoside + UDP + H(+)
daidzein + UDP-alpha-D-glucose = daidzein 7-O-beta-D-glucoside + UDP

Catalysed by UGT3A2, UGT3A1

alpha-D-glucose 1-phosphateReach from here →

genistein + UDP-alpha-D-glucose = genistein 7-O-beta-D-glucoside + UDP + H(+)
genistein + UDP-alpha-D-glucose = genistein 7-O-beta-D-glucoside + UDP + H(+)
alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose

Catalysed by UGT3A2, UGT3A1, GALTOne of 2 routes

UDP-alpha-D-galactoseReach from here →

genistein + UDP-alpha-D-glucose = genistein 7-O-beta-D-glucoside + UDP + H(+)
genistein + UDP-alpha-D-glucose = genistein 7-O-beta-D-glucoside + UDP + H(+)
alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose

Catalysed by UGT3A2, UGT3A1, GALTOne of 4 routes