Compound
genistein
An isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA topoisomerases, type II); activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 phase arrest in human and murine cell lines and inhibits protein-tyrosine kinase.
Structure
Loading the model…
- Class
- Organic compound, anion
- Formula
- C15H9O5
- Mass
- 269.232 g/mol
- Charge
- -1
- InChIKey
- TZBJGXHYKVUXJN-UHFFFAOYSA-M
- SMILES
- O=c1c(-c2ccc(O)cc2)coc2cc([O-])cc(O)c12
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
1 statement
1 statement · 1 reference database · Subject: genistein · Sources: Rhea
- genistein is a substrate of LCTProteinRhea RHEA:69687Inferred only
Reactions
4 reactions
CHEBI:31080genistein+water+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:36803CC BY 4.0Reference data
genistein+UDP-alpha-D-glucosegenistein 7-O-beta-D-glucoside+UDP+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:56056CC BY 4.0Reference data
genistein+reduced [NADPH--hemoprotein reductase]+dioxygenCHEBI:140306+oxidized [NADPH--hemoprotein reductase]+water+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:56108CC BY 4.0Reference data
genistein 7-O-beta-D-glucoside+watergenistein+beta-D-glucose
Catalysed by LCT
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:69687CC BY 4.0Reference data
On the label
Labelled products
25 products
Source: NIH DSLD · Ingredient: genistein · 25 products · Declared amount per serving: 10–250 mg (25 products)
25 labels state an amount0 do not
- Apex EnergeticsEstrovite (K-5)Soy Isoflavone · Genistein (Form: from Soy Isoflavone)10 mgper 1 Vegetarian Capsule(s)DSLD:82770
- Bayer CitacalCitracal plus Bone Density Builder27 mgper 2 Tablet(s)DSLD:17233
- Bronson LaboratoriesVegi Source25 mgper 2 Capsule(s)DSLD:9132
- Bronson LaboratoriesVegi Source25 mgper 2 Capsule(s)DSLD:9134
- Douglas LaboratoriesSenior Women's PackBonistein · Genistein (Form: from Bonistein)30 mgper 1 Packet(s)DSLD:5155
- GNC Natural BrandSoy Protein Natural Vanilla FlavorGenistein Note: (all forms) (7.80-23.40 mg)23.4 mgper 32 Gram(s)DSLD:2263
- GNC Natural BrandSoy Protein Unflavored/UnsweetenedGenistein Note: (all forms) (7.80-23.40 mg)23.4 mgper 15 Gram(s)DSLD:2262
- Harmonic InnerprizesCalMag Skeletal Rejuvenator10 mgper 1 Capsule(s)DSLD:19558
- Harmonic InnerprizesCalMag Skeletal Rejuvenator10 mgper 6 Capsule(s)DSLD:81544
- i-coolFor Menopause Plus Omega-330 mgper 1 Gelcap(s)DSLD:75068
- i-coolFor Menopause Plus Omega-330 mgper 1 Gelcap(s)DSLD:75746
- Nature's Bounty Optimal SolutionsTime Released Calcium 600 mg27 mgper 2 Tablet(s)DSLD:15885
Show the remaining 13
- Patient One MediNutritionalsMenoCoolgeniVida pure Genistein · Genistein (Form: as geniVida pure Genistein)30 mgper 2 Capsule(s)DSLD:69428
- PharmanexEstera Phase ISoy Isoflavone ext. · Genistein (Form: from 64% Soy Isoflavone Ext.)10 mgper 2 Softgel(s)DSLD:215061
- PharmanexEstera Phase ISoy Isoflavone ext. · Genistein (Form: from 64% Soy Isoflavone Ext.)10 mgper 2 Softgel(s)DSLD:27774
- PharmanexEstera Phase ISoy Isoflavone ext. · Genistein (Form: from 64% Soy Isoflavone Ext.)10 mgper 1 Softgel(s)DSLD:78831
- PharmanexEstera Phase IISoy Isoflavone extract · Genistein (Form: from Soy Isoflavone extract)15 mgper 1 Capsule(s)DSLD:176365
- PharmanexEstera Phase IIISoy Isoflavone ext. · Genistein (Form: from Soy Isoflavone ext.)55 mgper 2 Capsule(s)DSLD:27776
- ProCaps LaboratoriesUltimate Women's Wellness33 mgper 2 Capsule(s)DSLD:30044
- ProCaps LaboratoriesWomen's Wellness33 mgper 1 Capsule(s)DSLD:29995
- SuperSmartNatural Anti Aromatase SupportSophora japonica Extract · standardized to 98% genistein200 mgper 2 Tablet(s)DSLD:332400
- Swanson UltraGenistein 125 mgSophora japonica125 mgper 1 Veggie Capsule(s)DSLD:180972
- Swanson UltraStandardized Phytoestrogen Complex with EFAsSaphora japonica15 mgper 1 Softgel(s)DSLD:208193
- Vital NutrientsGenistein 125 mgGenistein rich Soy Isoflavone extract · Genistein (Form: from Genistein rich Soy Isoflavone extract Note: 80%)250 mgper 2 Vegetarian Capsule(s)DSLD:182572
- Vital NutrientsGenistein 125 mgSoy Extract · as extracted from soy standardized to 80% isoflavones250 mgper 2 Vegetarian Capsule(s)DSLD:304987
Label record: NIH Office of Dietary Supplements · CC0
Other names
1 name
Resolves to: genistein
- Systematic name
- 5-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-olate