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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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N-phosphocreatine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

6 compounds within 3 steps: 2 in 1, 1 in 2, 3 in 3

Does it reach a compound?

One step

creatinineReach from here →
1. creatine-phosphate to creatinine conversion
No catalyst recordedcytosol
creatineReach from here →
1. creatine kinase (creatine)
Catalysed by CKM, CKB, CKMT1A, CKMT2cytosolOne of 3 routes

Two steps

guanidinoacetateReach from here →
1. creatine kinase (creatine)
2. S-Adenosyl-L-methionine:guanidinoacetate N-methyltransferase
Catalysed by CKM, CKB, CKMT1A, CKMT2 and 1 morecytosolOne of 2 routes

Three steps

L-arginineReach from here →
Catalysed by CKM, CKB, CKMT1A, CKMT2 and 2 morecytosol
chlorine(.)Reach from here →
Catalysed by CKM and 1 more

cytosol, extracellular space

glycineReach from here →

creatine kinase (creatine)
S-Adenosyl-L-methionine:guanidinoacetate N-methyltransferase
L-Arginine:glycine amidinotransferase

Catalysed by CKM, CKB, CKMT1A, CKMT2 and 2 morecytosol