2,4-dinitrophenyl-S-glutathione

Three steps

• an S-substituted glutathioneReach from here →
  1. solute carrier organic anion transporter (cholate)
  2. cholate(in) + glutathione(in) + ATP + H2O = cholate(out) + glutathione(out) + ADP + phosphate + H(+)
  3. RX + glutathione = an S-substituted glutathione + a halide anion + H(+)

  Catalysed by SLCO1A2, SLCO1B3, ABCC4, GSTT4 and 22 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

• 19-hydroxyprostaglandin H1Reach from here →
  1. transport of prostaglandin E1 (cytosol to extracellular)
  2. prostaglandin-E synthase (prostaglandin E1)
  3. prostaglandin H1 + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxyprostaglandin H1 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

  Catalysed by SLCO1B1, PTGES, PTGES3, PTGES2 and 1 moreextracellular space, cytosol

• (13S)-hydroxy-(9Z,11E)-octadecadienoateReach from here →
  1. solute carrier organic anion transporter (cholate)
  2. cholate(in) + glutathione(in) + ATP + H2O = cholate(out) + glutathione(out) + ADP + phosphate + H(+)
  3. (13S)-hydroperoxy-(9Z,11E)-octadecadienoate + 2 glutathione = (13S)-hydroxy-(9Z,11E)-octadecadienoate + glutathione disulfide + H2O

  Catalysed by SLCO1A2, SLCO1B3, ABCC4, GPX1 and 3 moreextracellular space, cytosol, inner side of the membrane, outer side of the membrane