Compound

(R)-4'-phosphopantetheine

Pantetheine 4'-phosphate(2−) with D (R) configuration at the 2' position. The dianion formed from D-pantetheine 4'-phosphate by deprotonation of the phosphate group; major microspecies at pH 7.3.

Definition from ChEBI (CHEBI:61723), read 2026-09-23. CC BY 4.0.

CHEBI:61723ChEBI

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Structure

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A generated conformer of (R)-4'-phosphopantetheine — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C11H21N2O7PS
Mass: 356.337 g/mol
Charge: -2
InChIKey: JDMUPRLRUUMCTL-VIFPVBQESA-L
SMILES: CC(C)(COP(=O)([O-])[O-])[C@@H](O)C(=O)NCCC(=O)NCCS
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

2 entities

2 entities reached.

0 reported hops2 assembled from the scaffold

What the reference databases state

Statements

7 statements

7 statements · 1 reference database · Subject: (R)-4'-phosphopantetheine · Sources: Rhea

Order

(R)-4'-phosphopantetheine is converted to (R)-pantetheineCompoundRhea RHEA:22472Inferred only
(R)-4'-phosphopantetheine is converted to (R)-pantetheineCompoundRhea RHEA:68328Inferred only
(R)-pantetheine is converted to (R)-4'-phosphopantetheineCompoundRhea RHEA:22472Inferred only
(R)-4'-phosphopantetheine is converted to 3'-dephospho-CoACompoundRhea RHEA:19801Inferred only
N-[(R)-4-phosphopantothenoyl]-L-cysteine is converted to (R)-4'-phosphopantetheineCompoundRhea RHEA:16793Inferred only
(R)-4'-phosphopantetheine is a substrate of COASYProteinRhea RHEA:19801Inferred only
(R)-4'-phosphopantetheine is a substrate of PANK4ProteinRhea RHEA:68328Inferred only

Reactions

8 reactions

N-[(R)-4-phosphopantothenoyl]-L-cysteine+hydron(R)-4'-phosphopantetheine+carbon dioxide
Catalysed by PPCDC
Reaction pageLeft to rightBalanced
Rhea RHEA:16793CC BY 4.0Reference data
(R)-4'-phosphopantetheine+ATP(4-)+hydron3'-dephospho-CoA+diphosphate(3-)
Catalysed by COASY
Reaction pageLeft to rightBalanced
Rhea RHEA:19801CC BY 4.0Reference data
CHEBI:58555+holo-[citrate lyase ACP]acetyl-[citrate lyase ACP]+(R)-4'-phosphopantetheine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:20393CC BY 4.0Reference data
holo-[ACP]+waterapo-[ACP]+(R)-4'-phosphopantetheine+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:20537CC BY 4.0Reference data
(R)-pantetheine+ATP(4-)(R)-4'-phosphopantetheine+ADP(3-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:22472CC BY 4.0Reference data
coenzyme A(4-)+water(R)-4'-phosphopantetheine+adenosine 3',5'-bisphosphate+2hydron
Catalysed by NUDT19 or NUDT7 or NUDT8
Reaction pageLeft to rightBalanced
Rhea RHEA:64988CC BY 4.0Reference data
a 5'-end CoA-ribonucleoside in mRNA+watera 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA+(R)-4'-phosphopantetheine+2hydron
Catalysed by NUDT19 or NUDT7 or NUDT2 or NUDT8 or NUDT16 or NUDT15
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:67592CC BY 4.0Reference data
(R)-4'-phosphopantetheine+water(R)-pantetheine+hydrogenphosphate
Catalysed by PANK4
Reaction pageLeft to rightBalanced
Rhea RHEA:68328CC BY 4.0Reference data

Other names

2 names

Resolves to: (R)-4'-phosphopantetheine

Systematic name: N(3)-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonatooxy)butanoyl]-N-(2-sulfanylethyl)-beta-alaninamideN3-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonatooxy)butanoyl]-N-(2-sulfanylethyl)-β-alaninamide