knowcompoundstheobromine
Specimen compound organic compoundPlate I
Theobromine
- Formula
- C7H8N4O2
- Molar mass
- 180.167 g/mol
- ChEBI
- CHEBI:28946
- PubChem CID
- 5429
- InChIKey
- YAPQBXQYLJRXSA-UHFFFAOYSA-N
↑ raised 1 finding · – no difference found
01 · the evidence, ordered
What the evidence says
- Limited
Theobromine
36 compounds on the outer ring, not drawn
Keys
← → round a ring↑ ↓ out and inEnter selecte the outer ringf fit to view+ − zoomEsc clearclick a node to select it
02 · findings
What theobromine moved, and by how much
- MD mean difference. Brackets: the interval as reported.
- Dose studied: as its paper gave it.
- Evidence strength: computed from the study. How it is computed
- Flow-mediated dilationMoved: no difference foundEvidence: LimitedPaper: PMID 293306602019
- Who
- Overweight and obese men and women aged 45-70 years with HDL-C below the 50th percentile of the Dutch population; fasting measurement after 4 weeks of each treatment period
- Dose studied
- 500 mg theobromine per day in a 20 mL drink at breakfast for 4 weeks, versus placebo drink, crossover with 4-week washout
In the fasting condition, theobromine consumption did not change FMD, brachial artery diameter, and RHI.”
Quoted verbatim from Theobromine consumption does not improve fasting and postprandial vascular function in overweight and obese subjects.crossover · 4 weeksPermalink - HDL cholesterolMoved: raisesEffect, as reportedMD0.04[0.003 to 0.07]Evidence: LimitedPaper: PMID 297976952018
- Who
- Overweight and obese healthy men and women with HDL-C below the 50th percentile of the Dutch population; fasting values after 4 weeks of each treatment period
- Dose studied
- 500 mg theobromine per day for 4 weeks versus placebo, randomised double-blind crossover
Four weeks theobromine supplementation did not affect fasting cholesterol efflux capacity (+0.4 percentage point (pp); 95% CI: −2.81, 3.57; p = 0.81), but significantly increased HDL‐C concentrations (+0.04 mmol L−1; 95% CI: 0.003, 0.07; p < 0.05).”
Quoted verbatim from Theobromine Does Not Affect Fasting and Postprandial HDL Cholesterol Efflux Capacity, While It Decreases Fasting miR-92a Levels in Humans.crossover · 4 weeksPermalink
No row matches these filters.
No dose is advised.
- MD mean difference. Brackets: the interval as reported.
- Dose studied: as its paper gave it.
- Evidence strength: computed from the study. How it is computed
03 · identity
Structure
- Charge
- 0
- 2D depiction
- None stored
- SMILES
- Cn1cnc2c1c(=O)nc(=O)n2C
04 · on the label · 566 products
Labelled products
Source: NIH DSLD · Ingredient: theobromine · 566 products · Declared amount per serving: 1.9–400 mg
365 labels state an amount201 do not
- 'MericaRed, White & Boom Cherry Bootlegger100 mgper 11 gDSLD:327228
- 'MericaRed, White & Boom Napalm Jalapeno Margarita200 mgper 9.25 gDSLD:332822
- 'MericaRed, White & Boom Orange Man Bad100 mgper 11.25 gDSLD:332824
- 'MericaRed, White & Boom Sour Apple Rebellion100 mgper 11.5 gDSLD:332825
- 'MericaRed, White & Boom Teddy's Grape Melons100 mgper 11.35 gDSLD:332826
- 'MericaZ-Bomb Citrus Fallout100 mgper 9.55 gDSLD:332829
- 'Merica LabzF-Bomb Cat Scratch Fever100 mgper 7.55 gDSLD:316263
- 'Merica LabzF-Bomb F Your Feelings100 mgper 8.7 gDSLD:316265
- 'Merica LabzF-Bomb Fruit Cocktail100 mgper 8 gDSLD:316264
- 'Merica LabzF-Bomb Sour Pucker UP Buttercup100 mgper 8.75 gDSLD:327302
- 'Merica LabzF-Bomb Upside Down Pineapple100 mgper 7.75 gDSLD:316266
- 'Merica LabzRed White & Boom Back In Black Lemonade100 mgper 10.3 gDSLD:271113
Show the remaining 554Show the first 12
Label record: NIH Office of Dietary Supplements · CC0
05 · the record
Sources
21
papers screened for theobromine
- admitted
- 3
- read and discarded
- 8
- not read yet
- 10
- Documented interactions
- None reported
Sources cited
2 papers · 2 findings
1 admitted at screening, no finding yet