PapersPMID:29797695
Theobromine Does Not Affect Fasting and Postprandial HDL Cholesterol Efflux Capacity, While It Decreases Fasting miR-92a Levels in Humans.
What moved
1 findingHow to read these marks →- Increases HDL cholesterol
limited
“Four weeks theobromine supplementation did not affect fasting cholesterol efflux capacity (+0.4 percentage point (pp); 95% CI: −2.81, 3.57; p = 0.81), but significantly increased HDL‐C concentrations (+0.04 mmol L−1; 95% CI: 0.003, 0.07; p < 0.05).”
- Study
- crossover
- Duration
- 4 weeks
- Effect
- 0.04 mean difference, 95% CI 0.003 to 0.07
- Dose studied
- 500 mg theobromine per day for 4 weeks versus placebo, randomised double-blind crossover
- Population
- Overweight and obese healthy men and women with HDL-C below the 50th percentile of the Dutch population; fasting values after 4 weeks of each treatment period
Study record
- Design
- crossover trial
- Species
- human
- Population
- Healthy overweight and obese men and women
- Participants
- 44
- Comparator
- placebo
- Duration
- 28 days
- Endpoints measured
- 34