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Catalyst

theobromineFinding

Theobromine has no detected effect on flow-mediated dilation

no difference foundLimited evidenceFinding

01 · The sentence it was drawn from

“In the fasting condition, theobromine consumption did not change FMD, brachial artery diameter, and RHI.”
Quoted verbatim from Theobromine consumption does not improve fasting and postprandial vascular function in overweight and obese subjects.
This finding among the 32 findings on its endpoint

theobromine

Flow-mediated dilation

no difference found

Who
Overweight and obese men and women aged 45-70 years with HDL-C below the 50th percentile of the Dutch population; fasting measurement after 4 weeks of each treatment period
Dose studied
500 mg theobromine per day in a 20 mL drink at breakfast for 4 weeks, versus placebo drink, crossover with 4-week washout

Limited evidencePMID 29330660 · 2019

02 · The study

Study
crossover
Duration
4 weeks

Evidence, by strength

  • strong
  • moderate
  • limitedthis finding
  • very limited
  • insufficient

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZFKP9SCBH9RSJXPGKBGVCJ